Results 71 to 80 of about 6,509 (249)
Purpose: To report the first sequential cross-over treatment with the longest ophthalmic follow-up in a case of X-linked juvenile retinoschisis (XLRS) successfully treated with topical dorzolamide.
Razek Georges Coussa+1 more
doaj +1 more source
Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression [PDF]
Purpose. To evaluate hemodynamic parameters as possible predictors for glaucoma progression. Methods. An 18-month randomized double-masked cohort study including 30 open-angle glaucoma patients receiving fixed-combination treatment with Dorzolamide ...
Ehrlich, Rita+4 more
core +3 more sources
Treatment of Iris Hypoplasia Using Semiconductor Diode Laser in the Horse Under Standing Sedation
Objective: This study is aimed at describing two unique case presentations of iris hypoplasia and the use of semiconductor diode laser for treatment in the horse. Animals Studied: One 20‐year‐old American Quarter Horse gelding and one 11‐year‐old pony mare were studied.
Ethan M. Hefner+3 more
wiley +1 more source
Effects of dorzolamide hydrochloride 2% on the retinal circulation [PDF]
AbstractPurpose: To study the effect of a single dose of topical dorzolamide hydrochloride 2%, a carbonic anhydrase inhibitor, on the retinal circulation of normal subjects.Methods: Measurements of the effect of dorzolamide hydrochloride were performed in 20 normal subjects using bidirectional laser Doppler velocimetry and monochromatic fundus ...
Sameer Mathur+2 more
openaire +3 more sources
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf+4 more
doaj
New RP-HPLC Method Development and Validation for Dorzolamide in Ophthalmic Dosage Form
A reversed phase liquid chromatographic method with UV detection at 254 nm for dorzolamide assay in ophthalmic solutions was developed and validated. Chromatographic separation was achieved on a Zorbax SB C18 (250 mm × 4.6 mm, 5 µm) column kept at 30°C ...
Boovizhikannan Thangabalan+2 more
doaj +1 more source
Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion ...
Ruta Barsauskaite+6 more
doaj +1 more source
Whiter and Greener RP-HPLC Method for Simultaneous Determination of Dorzolamide, Brinzolamide, and Timolol Using Isopropanol as a Sustainable Organic Solvent in the Mobile Phase [PDF]
A sustainable reversed-phase chromatographic method has been developed and validated for the simultaneous determination of three active pharmaceutical ingredients, dorzolamide, brinzolamide, and timolol, used to treat glaucoma.
Abdelsamad, Khalid+2 more
core +1 more source
Amidation of Lasamide with piperazines led to potent and selective inhibitors of the human Carbonic Anhydrase (hCA, EC: 4.2.1.1) II isoform, whose role in glaucoma has been longtime validated. Insight into the interaction with the enzyme was gained through in silico studies.
Jaydeo T. Kilbile+14 more
wiley +1 more source
Intrafamilial Phenotype Variability in Two Male Siblings, With X-linked Juvenile Retinoschisis and Dorzolamide Treatment Effect in the Natural History of the Disease [PDF]
To investigate how genotype is related to phenotype and document correlations of genotype-phenotype with response of topical administration of dorzolamide in siblings affected with X-linked juvenile retinoschisis (XLRS).
CHRISTODOULOU, Panayiotis+4 more
core +1 more source