Results 71 to 80 of about 6,509 (249)

Treatment of cystic cavities in X-linked juvenile retinoschisis: The first sequential cross-over treatment regimen with dorzolamide

open access: yesAmerican Journal of Ophthalmology Case Reports, 2017
Purpose: To report the first sequential cross-over treatment with the longest ophthalmic follow-up in a case of X-linked juvenile retinoschisis (XLRS) successfully treated with topical dorzolamide.
Razek Georges Coussa   +1 more
doaj   +1 more source

Evaluation of Hemodynamic Parameters as Predictors of Glaucoma Progression [PDF]

open access: yes, 2011
Purpose. To evaluate hemodynamic parameters as possible predictors for glaucoma progression. Methods. An 18-month randomized double-masked cohort study including 30 open-angle glaucoma patients receiving fixed-combination treatment with Dorzolamide ...
Ehrlich, Rita   +4 more
core   +3 more sources

Treatment of Iris Hypoplasia Using Semiconductor Diode Laser in the Horse Under Standing Sedation

open access: yesCase Reports in Veterinary Medicine, Volume 2025, Issue 1, 2025.
Objective: This study is aimed at describing two unique case presentations of iris hypoplasia and the use of semiconductor diode laser for treatment in the horse. Animals Studied: One 20‐year‐old American Quarter Horse gelding and one 11‐year‐old pony mare were studied.
Ethan M. Hefner   +3 more
wiley   +1 more source

Effects of dorzolamide hydrochloride 2% on the retinal circulation [PDF]

open access: yesActa Ophthalmologica Scandinavica, 1997
AbstractPurpose: To study the effect of a single dose of topical dorzolamide hydrochloride 2%, a carbonic anhydrase inhibitor, on the retinal circulation of normal subjects.Methods: Measurements of the effect of dorzolamide hydrochloride were performed in 20 normal subjects using bidirectional laser Doppler velocimetry and monochromatic fundus ...
Sameer Mathur   +2 more
openaire   +3 more sources

A patient preference comparison of Azarga™ (brinzolamide/timolol fixed combination) vs Cosopt® (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension

open access: yesClinical Ophthalmology, 2008
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf   +4 more
doaj  

New RP-HPLC Method Development and Validation for Dorzolamide in Ophthalmic Dosage Form

open access: yesJournal of Analytical Methods in Chemistry, 2018
A reversed phase liquid chromatographic method with UV detection at 254 nm for dorzolamide assay in ophthalmic solutions was developed and validated. Chromatographic separation was achieved on a Zorbax SB C18 (250 mm × 4.6 mm, 5 µm) column kept at 30°C ...
Boovizhikannan Thangabalan   +2 more
doaj   +1 more source

Comparison of Intraocular Pressure, Blood Pressure, Ocular Perfusion Pressure and Blood Flow Fluctuations During Dorzolamide Versus Timolol Add-On Therapy in Prostaglandin Analogue Treated Glaucoma Subjects

open access: yesPharmaceuticals, 2012
Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion ...
Ruta Barsauskaite   +6 more
doaj   +1 more source

Whiter and Greener RP-HPLC Method for Simultaneous Determination of Dorzolamide, Brinzolamide, and Timolol Using Isopropanol as a Sustainable Organic Solvent in the Mobile Phase [PDF]

open access: yes
A sustainable reversed-phase chromatographic method has been developed and validated for the simultaneous determination of three active pharmaceutical ingredients, dorzolamide, brinzolamide, and timolol, used to treat glaucoma.
Abdelsamad, Khalid   +2 more
core   +1 more source

Lasamide Containing Sulfonylpiperazines as Effective Agents for the Management of Glaucoma Associated Symptoms

open access: yesChemMedChem, Volume 19, Issue 24, December 16, 2024.
Amidation of Lasamide with piperazines led to potent and selective inhibitors of the human Carbonic Anhydrase (hCA, EC: 4.2.1.1) II isoform, whose role in glaucoma has been longtime validated. Insight into the interaction with the enzyme was gained through in silico studies.
Jaydeo T. Kilbile   +14 more
wiley   +1 more source

Intrafamilial Phenotype Variability in Two Male Siblings, With X-linked Juvenile Retinoschisis and Dorzolamide Treatment Effect in the Natural History of the Disease [PDF]

open access: yes, 2019
To investigate how genotype is related to phenotype and document correlations of genotype-phenotype with response of topical administration of dorzolamide in siblings affected with X-linked juvenile retinoschisis (XLRS).
CHRISTODOULOU, Panayiotis   +4 more
core   +1 more source

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