Results 81 to 90 of about 6,509 (249)

Effects of anti-glaucoma medications on gangion cell survival: the DBA/2J mouse model [PDF]

, 2002
We studied whether several agents, approved or undergoing trials in human glaucoma, were effective in preventing ganglion cell loss in the DBA/2J mouse. Adult DBA/2J mice were treated with timolol, pilocarpine, brimonidine, dorzolamide, or NMDA-receptor ...
Naskar, Rita, Quinto, Kristine, Schuettauf, Frank, Zurakowski, David   +3 more
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton, Michael R. Gionfriddo, Gail B. Rattinger, Yuan Fang, Mia E. Lussier   +4 more
wiley   +1 more source

Elimination profile of low‐dose chlortalidone and its detection in hair for doping analysis—Implication for unintentional non‐therapeutic exposure

Drug Testing and Analysis, Volume 16, Issue 11, Page 1378-1383, November 2024.
An elimination of low‐dose chlortalidone and hydrochlorothiazide (HCTA) was conducted on five consecutive days in two volunteers. The urine concentrations were measured by LC–MS/MS. The chlortalidone concentration 10 days after the last ingestion of a sub‐therapeutic dose would have still caused an adverse analytical finding in an athlete's sample ...
Detlef Thieme, Kai Weigel, Patricia Anielski, Aniko Krumbholz, Frank Sporkert, Annekathrin M. Keiler   +5 more
wiley   +1 more source

Topical glaucoma medications − Possible implications on the meibomian glands

Acta Ophthalmologica, Volume 102, Issue 7, Page 735-748, November 2024.
Abstract One of the most common causes of blindness on a global scale is glaucoma. There is a strong association between glaucoma and increased intraocular pressure (IOP). Because of this, adequate IOP‐lowering is the most important treatment strategy, mostly through topical eyedrops.
Fredrik Fineide, Morten Magnø, Kristian Dahlø, Miriam Kolko, Steffen Heegaard, Jelle Vehof, Tor Paaske Utheim   +6 more
wiley   +1 more source

Considerations in glaucoma therapy: fixed combinations versus their component medications [PDF]

, 2009
Fixed combinations of medications that lower intraocular pressure (IOP) are increasingly used in the treatment of glaucoma and ocular hypertension and offer several potential advantages over combined use of the separate component medications including ...
Higginbotham, Eve J
core   +2 more sources

Latanoprost and Dorzolamide for the Treatment of Pediatric Glaucoma: The Glaucoma Italian Pediatric Study (Gipsy), Design and Baseline Characteristics [PDF]

, 2016
INTRODUCTION: To investigate the efficacy of a treatment strategy with latanoprost and dorzolamide in primary pediatric glaucoma patients partially responsive to surgery. METHODS: Single arm, prospective, interventional multicenter study.
Biagioli, Elena, Galli, Francesca, Hollander, Lital, Katsanos, Andreas, Longo, Antonio, Poli, Davide, Quaranta, Luciano, Riva, Ivano, Rulli, Eliana, Torri, Valter, Uva, Maurizio G., Weinreb, Robert N.   +11 more
core   +2 more sources

Topical dorzolamide for macular holes: A randomised, double‐blind, placebo‐controlled trial

Clinical &Experimental Ophthalmology, Volume 52, Issue 8, Page 870-879, November 2024.
Abstract Background To assess topical dorzolamide as medical therapy for idiopathic full‐thickness macular holes (FTMHs). Methods Randomised, double‐blinded, placebo‐controlled, single‐centre clinical trial involving 32 patients with idiopathic small FTMHs (<400 μm).
Yong Min Lee, Bobak Bahrami, Duleepa Baranage, Premala Devi Sivagurunathan, Wilson Wong, Montserrat Maria Bausili, Surbhi Agrawal, Jagjit Singh Gilhotra, Shane Durkin, David Sia, Dinesh Selva, Stewart Lake, Robert J. Casson, Weng Onn Chan   +13 more
wiley   +1 more source

Effects of topical levobunolol or fixed combination of dorzolamide-timolol or association of dorzolamide-levobunolol on intraocular pressure, pupil size, and heart rate in healthy cats Efeitos da aplicação tópica do levobunolol, da combinação fixa de dorzolamidatimolol ou da associação de dorzolamida com levobunolol sobre a pressão intra-ocular, o diâmetro pupilar e a freqüência cardíaca em gatos saudáveis

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
The effects of topical levobunolol with the fixed combination of 2% dorzolamide-0.5% timolol and the association of 2% dorzolamide with 0.5% levobunolol on intraocular pressure (IOP), pupil size (PS), heart rate (HR), and conjunctival hyperemia in ...
A.P. Ribeiro, D.P. Junior, T. Champion, M.A. Brunetto, A.A. Camacho, J.L. Laus   +5 more
doaj   +1 more source

Study of prescription pattern of antiglaucoma drugs used in treatment of primary open angle glaucoma in ophthalmology outpatient department of a tertiary care hospital [PDF]

, 2018
Background: In view of the high prevalence rates and the fact that medication is the primary line of treatment in POAG, an understanding of prescribing patterns can provide an insight into rational use of antiglaucoma drugs.Methods: This prospective ...
Advani, Manjari, Jadhao, Trupti
core   +2 more sources

Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The β-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Clostridium perfringens (CpeCA) was recently characterised kinetically and for its anion inhibition profile. In the search of effective CpeCA inhibitors, possibly useful to inhibit
Daniela Vullo, R. Siva Sai Kumar, Andrea Scozzafava, James G. Ferry, Claudiu T. Supuran   +4 more
doaj   +1 more source