Results 201 to 210 of about 78,023 (273)

Dosage compensation and sex-specific epigenetic landscape of the X chromosome in the pea aphid [PDF]

, 2017
Gautier Richard, Fabrice Legeai, Nathalie Prunier‐Leterme, Anthony Bretaudeau, Denis Tagu, Julie Jaquiéry, Gaël Le Trionnaire   +6 more
openalex   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species. [PDF]

Elife, 2023
Yang Q, Lo TW, Brejc K, Schartner C, Ralston EJ, Lapidus DM, Meyer BJ.   +6 more
europepmc   +1 more source

Combined effects of dosage compensation and incomplete dominance on gene expression in triploid cyprinids [PDF]

, 2019
Li Ren, Xiaojing Yan, Liu Cao, Jiaming Li, Xueyin Zhang, Xin Gao, Jia Liu, Jialin Cui, Shaojun Liu   +8 more
openalex   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Effect of heterozygous deletions on phenotypic changes and dosage compensation in Arabidopsis thaliana. [PDF]

Sci Rep
Ikoma T, Nishijima R, Ikeda M, Ishii K, Nagalla AD, Abe T, Kazama Y.   +6 more
europepmc   +1 more source

Dual roles for nuclear RNAi Argonautes in Caenorhabditis elegans dosage compensation. [PDF]

Genetics, 2022
Davis MB, Jash E, Chawla B, Haines RA, Tushman LE, Troll R, Csankovszki G.   +6 more
europepmc   +1 more source

Additional file 2 of Sex chromosome dosage compensation in a sex reversing skink is not influenced by sexual phenotype

Benjamin J. Hanrahan, J King Chang, Ashley M. Milton, Nicholas C. Lister, Duminda S. B. Dissanayake, J. W. Hammond, Andre L. M. Reis, Ira W. Deveson, Aurora Ruiz-Herrera, Hardip R. Patel, Qi Zhou, Arthur Georges, Niki Vontzou   +12 more
openalex   +1 more source

Dosage compensation in human pre‐implantation embryos: X‐chromosome inactivation or dampening? [PDF]

, 2018
Roni Saiba, Maniteja Arava, Srimonta Gayen   +2 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source