Results 211 to 220 of about 78,023 (273)

Role of X chromosome and dosage-compensation mechanisms in complex trait genetics. [PDF]

Am J Hum Genet
Fu Y, Kenttämies A, Ruotsalainen S, Pirinen M, Tukiainen T.   +4 more
europepmc   +1 more source

Rapid Evolution of Complete Dosage Compensation in Poecilia. [PDF]

Genome Biol Evol, 2021
Metzger DCH, Sandkam BA, Darolti I, Mank JE.   +3 more
europepmc   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

Dynamic Spatial-temporal Expression Ratio of X Chromosome to Autosomes but Stable Dosage Compensation in Mammals. [PDF]

Genomics Proteomics Bioinformatics, 2023
Qian SH, Xiong YL, Chen L, Geng YJ, Tang XM, Chen ZX.   +5 more
europepmc   +1 more source

Additional file 8 of Aneuploidy-induced proteotoxic stress can be effectively tolerated without dosage compensation, genetic mutations, or stress responses

, 2020
Katherine E. Larrimore, Natalia S. Barattin-Voynova, David W. Reid, Davis Ng   +3 more
openalex   +1 more source

The segmentation generuntis needed to activateSex-lethal, a gene that controls sex determination and dosage compensation inDrosophila [PDF]

, 1992
Miguel Torres, Lucas Sánchez
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

DOSAGE COMPENSATION OF GENES ON THE LEFT AND RIGHT ARMS OF THE X CHROMOSOME OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA WILLISTONI [PDF]

, 1974
Irene Abraham, John C. Lucchesi
openalex   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation. [PDF]

Elife
Babosha V, Klimenko N, Revel-Muroz A, Tikhonova E, Georgiev P, Maksimenko O.   +5 more
europepmc   +1 more source