Results 281 to 290 of about 1,171,051 (326)

The Impact of Chernobyl on Health and Labour Market Performance in the Ukraine [PDF]

H. Lehmann, J. Wadsworth
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Parallel evolution of X chromosome-specific SMC complexes in two nematode lineages

Aharonoff A, Kim J, Washington A, Ercan S.   +3 more
europepmc   +1 more source

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The X chromosome dosage compensation program during the development of cynomolgus monkeys

Science, 2021
Description X chromosome activity in primates Mammalian X and Y sex chromosomes differ greatly in structure and gene content. Therefore, mechanisms are in place to ensure that there is balanced gene dosage between the X chromosome and autosomes and ...
I. Okamoto, Tomonori Nakamura, Kotaro Sasaki, Y. Yabuta, C. Iwatani, H. Tsuchiya, Shin-ichiro Nakamura, M. Ema, Takuya Yamamoto, M. Saitou   +9 more
semanticscholar   +3 more sources

Dosage Compensation

Resonance, 2021
R. Raman
semanticscholar   +3 more sources

Dosage Compensation of the X Chromosome: A Complex Epigenetic Assignment Involving Chromatin Regulators and Long Noncoding RNAs.

Annual Review of Biochemistry, 2018
X chromosome regulation represents a prime example of an epigenetic phenomenon where coordinated regulation of a whole chromosome is required. In flies, this is achieved by transcriptional upregulation of X chromosomal genes in males to equalize the gene
Maria Samata, A. Akhtar
semanticscholar   +3 more sources

Incomplete transcriptional dosage compensation of chicken and platypus sex chromosomes is balanced by post-transcriptional compensation

bioRxiv, 2023
Heteromorphic sex chromosomes (XY or ZW) present problems of gene dosage imbalance between the sexes, and with the autosomes. Mammalian X chromosome inactivation was long thought to imply a critical need for dosage compensation in vertebrates.
Nicholas C. Lister, A. M. Milton, H. Patel, S. Waters, Benjamin J. Hanrahan, Kim L. McIntyre, Alexandra M. Livernois, Lee Kian Wee, A. Ringel, S. Mundlos, Michael I. Robson, Linda Shearwin-Whyatt, F. Grützner, J. A. Marshall Graves, A. Ruiz-Herrera, P. Waters   +15 more
semanticscholar   +1 more source

What dosage compensation?

Nature Reviews Genetics, 2010
Tanita Casci
openaire   +4 more sources

Evolution of dosage compensation

Chromosome Research, 1996
In polytene chromosome squashes from the fruit fly Drosophila melanogaster, the single, dosage-compensated X chromosome in males can be distinguished from the autosomes by the presence of an isoform of histone H4 acetylated at lysine 16, H4.Ac16. We have used H4.Ac16 as a marker to examine the evolving relationship between dosage compensation and sex ...
M, Steinemann, S, Steinemann, B M, Turner   +2 more
openaire   +2 more sources

Dosage compensation goes global

Current Opinion in Genetics & Development, 2007
In many organisms, females have two X chromosomes whereas males have just one. This natural X chromosome monosomy is not lethal, because of dosage compensation. Although numerous elegant genetic, biochemical and cytological experiments have been used to build up the mechanistic framework describing this specialized transcriptional control, dosage ...
Yu, Zhang, Brian, Oliver
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Chromatin Remodeling in Dosage Compensation

Annual Review of Genetics, 2005
In many multicellular organisms, males have one X chromosome and females have two. Dosage compensation refers to a regulatory mechanism that insures the equalization of X-linked gene products in males and females. The mechanism has been studied at the molecular level in model organisms belonging to three distantly related taxa; in these organisms ...
John C, Lucchesi, William G, Kelly, Barbara, Panning   +2 more
openaire   +2 more sources