A Nonparametric Method for the Derivation of α/β Ratios from the Effect of Fractionated Irradiations [PDF]
Multifractionation isoeffect data are commonly analysed under the assumption that cell survival determines the observed tissue or tumour response, and that it follows a linear-quadratic dose dependence.
A.M. Kellerer +19 more
core +1 more source
Correlation between cardiometabolic index and stroke in middle-aged and older adults
Objective To explore the relationship between cardiac metabolic index (CMI) and stroke in middle-aged and elderly individuals based on a large sample cohort study. Methods Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS)
YU Yang, SHA Ou
doaj +1 more source
Association between dietary magnesium intake and risk of hypertension in Chinese adults
BackgroundMagnesium plays an important physiological role in human, but the association between dietary magnesium intake and the risk of hypertension is unclear. Few studies have reported the dose-response relationship in Chinese population.
Liusen WANG +8 more
doaj +1 more source
Ciprofol, a novel γ-aminobutyric acid receptor agonist, outperforms propofol with minimal cardiovascular effects, higher potency, reduced injection pain, and a broader safety margin.
Min Liao +5 more
doaj +1 more source
Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity [PDF]
BACKGROUND: It is important to quantify the dose response for a drug in phase 2a clinical trials so the optimal doses can then be selected for subsequent late phase trials.
AE Raftery +17 more
core +2 more sources
Dose–Response Relationship Between BMI and Hyperuricemia
Lu Yang,1 Zhen’an He,2 Xuan Gu,3 Hao Cheng,4 Lin Li5 1Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital City, Hangzhou, Zhejiang Province, People’s Republic of China; 2Shaanxi Institute of Medical Device Quality Supervision and Inspection,
Yang L, He Z, Gu X, Cheng H, Li L
doaj
Dose-response relationship and low dose extrapolatioin in chemical carcinogenesis [PDF]
Data supporting various dose-response relationships in chemical carcinogenesis are summarized. General principles are derived to explain the relationships between exposure dose, DNA adduct level, induction of genetic changes, and tumor incidence.
Lutz, Werner K.
core
Association between exposure to noise and risk of hypertension: A meta-analysis of observational epidemiological studies [PDF]
Background and Objective: An increasing amount of original studies suggested that exposure to noise could be associated with the risk of hypertension, but the results remain inconsistent and inconclusive.
Cao, Shiyi +9 more
core +1 more source
Estimating the impact of city-wide Aedes aegypti population control: An observational study in Iquitos, Peru. [PDF]
During the last 50 years, the geographic range of the mosquito Aedes aegypti has increased dramatically, in parallel with a sharp increase in the disease burden from the viruses it transmits, including Zika, chikungunya, and dengue.
Astete, Helvio +12 more
core +2 more sources
BackgroundTo compare the effects of various exercise modalities on intelligence and determine the optimal exercise dose for children and adolescents.MethodsA systematic review and Bayesian network meta-analysis following PRISMA guidelines was conducted ...
Yan Wang +9 more
doaj +1 more source

