Results 41 to 50 of about 978,397 (252)

Dose-Response Relationships in Human Experimental Exposure to Solvents

, 2006
Previous studies carried out in the field of experimental toxicology have shown evidence of biphasic dose-response relationships for different experimental models, end-points and chemicals tested.
Giovanni Carelli, Ivo Iavicoli, Alessandro Marinaccio   +2 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Dose-Response Calculator for ArcGIS

, 2011
The Dose-Response Calculator for ArcGIS is a tool that extends the Environmental Systems Research Institute (ESRI) ArcGIS 10 Desktop application to aid with the visualization of relationships between two raster GIS datasets.
Leu M., Hanser, S.E., Nielsen S.E., Aldridge C.L.   +3 more
core   +1 more source

Rat mammary carcinogenesis following neutron- or X-radiation [PDF]

, 1974
Female 61 to 63 - day - old Sprague-Dawley rats were exposed once to a single dose of either 0.43 - MeV neutrons or 250 - kVX - rays . For neutrons 23 rats were exposed in plastic tubes rotated around and 31 c m from a water-cooled tritium impregnated ...
Rossi, H. H., Mills, R. E., Kellerer, Albrecht M., Goodman, L. J., Rao, A. R., Bond, V. P., Brown, R. D., Shellabarger, C. J., Shanley, J. P.   +8 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dose-response relationship between tooth loss and risk of cardiovascular disease.

, 2018
Dose-response relationship between tooth loss and risk of cardiovascular disease.
Mi Zhang (42795), Xiao Dong (244652), Quan Wang (31224), Haijun Xu (215417), Jiajuan Chen (5029475), Yunjie Wei (5029478), Zhen Gao (609801), Fei Cheng (315348), Fen Qin (4067335)   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dose-response relationship between tobacco smoking and the risk of composite TB treatment outcomes.

, 2019
Dose-response relationship between tobacco smoking and the risk of composite TB treatment outcomes.
Nikhil Gupte (189999), Nishi Suryavanshi (375258), Kannan Thiruvengadam (796402), Mandar Paradkar (5579405), Padmapriyadarshini Chandrasekaran (6996584), Senthanro Ovung (848525), Shrutha Sivakumar (7109627), Sanjay Gaikwad (6996593), Jonathan E. Golub (296079), Andrea Deluca (4766721), Vidya Mave (541004), Beena Elizabeth Thomas (848523), Shri Vijay Bala Yogendra Shivakumar (796407), Akshay N. Gupte (4433362), Kavitha Dhanasekaran (5579402), Gomathi Narayan Sivaramakrishnan (5579408), Rani S. (7109624), Rewa Kohli (307713), Dileep Kadam (4064449), Neeta Pradhan (5579411), Anju Kagal (375252), C. K. Dolla (7109630), Amita Gupta (21762)   +22 more
core   +1 more source

A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe

Frontiers in Pharmacology, 2021
Aims: Cardiovascular outcome trials with anti-diabetic drugs suggest that additional cardiovascular benefit can be achieved independent of improving glycaemic control.
Jeroen V. Koomen, Jeroen V. Koomen, Jasper Stevens, Margje H. Monster-Simons, Margje H. Monster-Simons, Hiddo J. L. Heerspink, Peter G. M. Mol, Peter G. M. Mol   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source