Background The dose‒response relationship-based relative risk (RR) of smoking exposure could better predict the risk of lung cancer than the dichotomous RR.
Feiling Ai +3 more
doaj +1 more source
Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. [PDF]
In part A of this study, patients were randomised to cohorts receiving darbepoetin alfa at doses of 0.5 to 8.0 m.c.g x kg(-1) x wk(-1) or to a control group receiving epoetin alfa at an initial dose of 150 U x kg(-1) three times weekly.
Armstrong, S +10 more
core +2 more sources
Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors [PDF]
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors ...
Cohen, B. N. +5 more
core +2 more sources
A Poisson Regression Model for Female Radium Dial Workers [PDF]
A Poisson regression model with interaction terms was applied to study the dose response relationship for radium-induced skeletal cancers. The model showed that the expected frequency count of bone tumors depended not only on the logarithmic dose and the
Lee, Tze-San
core +2 more sources
Background: Generally, oral immunotherapy (OIT) aims for daily administration. Recently, the efficacy of treatment with OIT at a low dose has been reported.
Kiyotake Ogura +20 more
doaj +1 more source
Dose response relationship in anti-stress gene regulatory networks. [PDF]
To maintain a stable intracellular environment, cells utilize complex and specialized defense systems against a variety of external perturbations, such as electrophilic stress, heat shock, and hypoxia, etc.
Qiang Zhang, Melvin E Andersen
doaj +1 more source
The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men [PDF]
Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out
Lennon, L. +6 more
core +1 more source
Evaluation of mutagenicity of zinc oxide nanoparticles by Pig-a mutation assay in vivo
ObjectiveThe genotoxicity of zinc oxide nanoparticles (ZnO NPs) in rats was determined by Pig⁃a mutation assay in vivo.MethodsCombined with 28-day oral toxicity test, male SD rats were given ZnO NPs by oral administration for 28 days, at doses of 0, 14 ...
CHENG Xueqing +4 more
doaj +1 more source
Dose-response relationship for breast cancer induction at radiotherapy dose
Purpose Cancer induction after radiation therapy is known as a severe side effect. It is therefore of interest to predict the probability of second cancer appearance for the patient to be treated including breast cancer.
Gruber Günther +5 more
doaj +1 more source
The Export-Growth Relationship : Estimating a Dose-Response Function [PDF]
The relationship between individual firms' export behaviour and firm performance has been studied extensively in the economic literature. However, most studies from the field of economics only distinguish between exporting and non-exporting companies ...
Fryges, Helmut
core +2 more sources

