Results 1 to 10 of about 7,945,859 (267)

Nitrogen Critical Loads: Critical Reflections on Past Experiments, Ecological Endpoints, and Uncertainties

open access: yesDose-Response, 2022
Nitrogen Critical Loads (NCL), as purported ecological dose-response outcomes for nitrogen deposition from anthropogenic sources, play a central role in environmental policies around the world.
William M. Briggs, Jaap C. Hanekamp
doaj   +1 more source

Protective Effects of Polydatin on Reproductive Injury Induced by Ionizing Radiation

open access: yesDose-Response, 2022
The reproductive system is vulnerable to ionizing radiation, which is a hot research topic at present. We tested the effect of polydatin on spermatocytes(GC-1 cells) after X-ray irradiation.
Jin Gao   +6 more
doaj   +1 more source

Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus—Evidence From the Literature

open access: yesDose-Response, 2023
Apart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory ...
Saima Naz Mohsin MS   +4 more
doaj   +1 more source

Low-Dose Berberine Attenuates the Anti-Breast Cancer Activity of Chemotherapeutic Agents via Induction of Autophagy and Antioxidation

open access: yesDose-Response, 2020
Berberine (BBR), a major active component of Rhizoma coptidis , is one of the most promising agents for breast cancer adjuvant therapy. It is well accepted that BBR could exhibit remarkable anticancer efficacy with few side effects, and when treated with
Bing Han   +4 more
doaj   +1 more source

Expression of Caveolin-1 Is Associated With Thyroid Function in Patients With Human Papillary Thyroid Carcinoma

open access: yesDose-Response, 2020
Objective: The aim of this study was to evaluate the levels of caveolin-1 in thyroid follicular epithelial cells of papillary thyroid cancer, follicular thyroid cancer, and nonmalignant thyroid nodule benign follicular adenoma, as well as to explore the ...
Jingyi Zhang   +7 more
doaj   +1 more source

Reasons for Undergoing CT During Childhood: Can CT-Exposed and CT-Naive Populations Be Compared?

open access: yesDose-Response, 2020
Several epidemiological studies suggested an increased risk of cancer and other tumors in individuals undergoing computed tomography (CT) examination during childhood; however, it was questioned whether the group undergoing CT was comparable to that not ...
Shunsuke Shibata   +5 more
doaj   +1 more source

Toxic Responses Induced at High Doses May Affect Benchmark Doses

open access: yesDose-Response, 2020
To derive reference points (RPs) for health-based guidance values, the benchmark dose (BMD) approach increasingly replaces the no-observed-adverse-effect level approach.
Jürg A. Zarn   +2 more
doaj   +1 more source

The Effect of Exposure to Bisphenol A on Spermatozoon and the Expression of Tight Junction Protein Occludin in Male Mice

open access: yesDose-Response, 2020
Although bisphenol A (BPA) has been associated with impaired spermatogenesis, the mechanisms remain unclear. Tight junction occludin plays important roles in spermatogenesis.
Tingshuai Cao   +6 more
doaj   +1 more source

Assessment of the Validity of Carbon Ion Irradiation for C6 Gliomas in Rats

open access: yesDose-Response
Purpose Application of energy-spectrum computed tomography (CT) to assess specific efficacy of and response to carbon ion radiotherapy (CIRT) of C6 gliomas in rats.
Yufeng Li   +6 more
doaj   +1 more source

Tritiated Water Induces Toxicity in Human Umbilical Vein Vascular Endothelial Cells via IL8

open access: yesDose-Response, 2020
We aimed to determine the toxic effects of tritiated water (HTO) on 12 generations (T1-T12) of human umbilical vein vascular endothelial cells (HUVECs) and elucidate the underlying mechanisms.
Hong-Bin Yan   +11 more
doaj   +1 more source

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