Results 11 to 20 of about 7,945,859 (267)

Buspirone Dose-Response on Facilitating Forelimb Functional Recovery in Cervical Spinal Cord Injured Rats [PDF]

, 2021
Buspirone, widely used as a neuropsychiatric drug, has also shown potentials for motor function recovery of injured spinal cord. However, the optimum dosages of such treatment remain unclear.
Zheng, Yong-Ping, Edgerton, VR, Alam, Monzurul, Zheng, YP, Universitat Autònoma de Barcelona, Edgerton, Victor, Li, Shuai, Alam, M, Ahmed, Rakib Uddin, Ahmed, RU, Li, S   +10 more
core   +1 more source

Sub-Chronic Oral Exposure to Iridium (III) Chloride Hydrate in Female Wistar Rats: Distribution and Excretion of the Metal [PDF]

, 2012
Iridium tissue distribution and excretion in female Wistar rats following oral exposure to iridium (III) chloride hydrate in drinking water (from 1 to 1000 ng/ml) in a sub-chronic oral study were determined.
Mattei, Daniela, Iavicoli, Ivo, Antonio Bergamaschi, Daniela Mattei, Marcelo Enrique Conti, Alimonti, Alessandro, Anna Pino, Bocca, Beatrice, Fontana, Luca, Ivo Iavicoli, CONTI, Marcelo Enrique, Luca Fontana, Beatrice Bocca, Bergamaschi, Antonio, Alessandro Alimonti, Pino, Anna   +15 more
core   +1 more source

Dose calculations for [¹³¹I] meta-iodobenzylguanidine-induced bystander effects

, 2014
Targeted radiotherapy is a potentially useful treatment for some cancers and may be potentiated by bystander effects. However, without estimation of absorbed dose, it is difficult to compare the effects with conventional external radiation treatment ...
R. J. Mairs, Seymour, C B, M. D. Gow, Mairs, R J, C. B. Seymour, Gow, M.D., Mothersill, C.E., Seymour, C.B., C. E. Mothersill, Mairs, R.J., M. Boyd, W. V. Prestiwch, Mothersill, C E, Prestiwch, W V, Prestiwch, W.V., Boyd, Marie, Boyd, M., Gow, M D   +17 more
core   +1 more source

Compound optimal designs for percentile estimation in dose-response models with restricted design intervals [PDF]

, 2005
In dose-response studies, the dose range is often restricted due to ethics concerns over drug toxicity and/or efficacy, particularly when human subjects are involved.
Stefanie Biedermann, Zhu, Wei, Dette, Holger, Holger Dette, Biedermann, Stefanie, Wei Zhu   +5 more
core   +2 more sources

Ozone as U-shaped dose responses molecules (Hormetins)

, 2010
Redox environment involves a broad network of pro-oxidant and antioxidant components. Health benefit or damage can be induced as a consequence of an adaptive cellular stress response.
G. Martínez-Sánchez, A. Giuliani, G. Pérez Davison, L. Re, G. Pérez-Davison, G. Martinez Sanchez   +5 more
core   +1 more source

Comparison of X-ray and gamma-ray dose-response curves for pink somatic mutations in Tradescantia clone 02 [PDF]

, 1976
Microdosimetric data indicate that the mean specific energy,zeta, produced by individual charged particles from X rays and gamma rays is different for the two radiation qualities by nearly a factor of two.
Mills, R. E., Kellerer, Albrecht M., Sparrow, A. H., Underbring, A. G.   +3 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Utilizing of Seaweed for Eco-friendly Synthesis of Nickel Cobalt Nanoparticles and Assessment of its Cytotoxic Effects on Human Liver and Colon Cancer Cells

Dose-Response
In this study we used biosynthesis methods to create bimetallic nickel cobalt nanoparticles (Ni-Co NPs) utilizing seaweed. Before exposure to target cells, the characterization of Ni-Co NPs is done by UV-Vis spectrophotometry, EDX, SEM, TEM, the shape of
Eman A. Alanazy, Daoud Ali, Mohammed H. A. Almarzoug, Khadijah N. Yaseen, Bader O. Almutairi, Saad Alkahtani, Badr A. Aldahmash, Saud Alarifi   +7 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source