Results 21 to 30 of about 7,945,859 (267)

Nrf2 Deficiency Brings About Increased Sensitive to IR and 7,12-dimethylbenz(a)anthracene and Leukemia Predisposition

Dose-Response
Purpose Nuclear factor erythroid 2-related factor 2 (Nrf2) is a crucial cytoprotective protein that shields cells from electrophilic and oxidative stress.
Mingxin Dong, Ping Yang, Xinyu Zhang, Shasha Nie, Xiaohui Sun   +4 more
doaj   +1 more source

Use CT Imaging to Predict the Short-Term Outcome of Concurrent Chemoradiotherapy in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

Dose-Response, 2019
Objective: To extract the computed tomography (CT) imaging features of the primary lesions in patients with advanced esophageal squamous cell carcinoma (ESCC) and to study whether these imaging features can predict the short-term outcome after concurrent
Xiaolan Cao, Xindi Li, Xiaoyue Wang, Jinghao Duan, Shouhui Zhu, Haiyan Zeng, Yong Yin, Shuanghu Yuan, Xudong Hu   +8 more
doaj   +1 more source

Dose-response of the drug in rats.

, 2023
(A, D) show the estimated ki and kef grouped by drug dose. (B, E) show dose-response plots for ki and kef, respectively. The black curve is the dose response function and the gray lines shows the IC50 point.
Christian Simonsson (13775710), Peter Lundberg (307397), Gunnar Cedersund (271543), Nils Dahlström (584690), Markus Karlsson (3463568)   +4 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Salidroside Pre-Treatment Inhibits Hypertensive Renal Injury and Fibrosis Through Inhibiting Wnt/β-Catenin Pathway

Dose-Response
Objectives This study aimed to explore the protective effects and underlying mechanisms of salidroside (SAL) in angiotensin II (Ang II)-induced hypertensive renal injury and fibrosis, using in vivo and in vitro models. Methods In this study, we generated
Jie Zhu, Liang Li, Yuting Luan, Ziqing Zhang, Yi Wang, Zhenyu Xu   +5 more
doaj   +1 more source

Effects of Radon From Hot Springs on Lymphocyte Subsets in Peripheral Blood

Dose-Response, 2020
Objective: To analyze changes in immune functions by detecting lymphocyte subsets in the peripheral blood of residents in the vicinity of radon from hot springs.
Chunnan Piao, Mei Tian, Hongjun Gao, Yanxiao Gao, Jianlei Ruan, Lina Wu, Gang Gao, Lirong Yi, Jianxiang Liu   +8 more
doaj   +1 more source

Code for Bayesian inference of dose-response curve parameters

, 2016
<p>This is an archived version of the initial release of dose-response-fitting to co-incide with a Wellcome Open Research article.</p> <p>The latest version can be found at: <a href="https://github.com/mirams/dose-response-fitting ...
Bardenet, Remi, Mirams, Gary, Gavaghan, David (8181900), Mirams, Gary (8181891), Gavaghan, David, Johnstone, Ross, Bardenet, Remi (8181897), Johnstone, Ross (8181894)   +7 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Assessment of Photo Apoptotic and Genotoxicity of Nalidixic Acid on the Mouse Fibroblast Cell Line Under Ambient Environmental Intensity of UV-B Irradiation

Dose-Response
Objectives: Nalidixic acid has been used as a potent antibiotic drug in the biomedical sciences. In this study, we assessed photochemical properties of nalidixic acid as well as its effect for photocytotoxicity, apoptosis, and genotoxicity on the mouse ...
Daoud Ali, Bader O. Almutairi, Anis Ahmed, Mohammed H. Almarzoug, Saud Alarifi, Saad Alkahtani   +5 more
doaj   +1 more source

Interpreting 'Dose-Response' Curves Using Homeodynamic Data: With an Improved Explanation for Hormesis

, 2009
A re-interpretation of the ‘Dose-Response’ curve is given that accommodates homeostasis. The outcome, or overall effect, of toxicity is the consequence of toxicity that is moderated by homeodynamic responses.
Stebbing, ARD, A.R.D. Stebbing
core   +1 more source