Results 91 to 100 of about 7,945,859 (267)
Biphasic Dose Response in Low Level Light Therapy
The use of low levels of visible or near infrared light for reducing pain, inflammation and edema, promoting healing of wounds, deeper tissues and nerves, and preventing cell death and tissue damage has been known for over forty years since the invention
Michael R. Hamblin +3 more
core +1 more source
An examination of dose in mindfulness-based programs and Mindfulness practice through a dose-response meta-regression and randomised controlled experiments [PDF]
Mindfulness research has grown exponentially in recent years including research with various doses related to mindfulness-based programs (MBPs) and mindfulness practice.
Strohmaier, S.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The application of nanotechnology to traditional Chinese medicine (TCM) enabled the development of Chinese medicine in the international society. The pharmacodynamics of TCM is not only depending on its chemical constituents but also related to its ...
Guojun Yan +8 more
doaj +1 more source
Radiation-Induced Bystander Effects: Evidence for an Adaptive Response to Low Dose Exposures?
This paper reviews our current knowledge of the mechanisms underlying the induction of bystander effects by low dose, low-LET ionizing radiation and discusses how they may be related to observed adaptive responses or other protective effects of low dose ...
Carmel Mothersill, Colin Seymour
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Nonlinear Response for Neoplastic Transformation following Low Doses of Low Let Radiation
There are now several independent studies that indicate that the dose-response for the endpoint of radiation-induced neoplastic transformation in vitro is non-linear for low linear energy transfer (LET) radiation. At low doses (
J. Leslie Redpath
doaj +1 more source
The hormesis phenomena or J-shaped dose response have been accepted as a common phenomenon regardless of the involved biological model, endpoint measured and chemical class/physical stressor. This paper first introduced a mathematical dose response model
Yingjie Wu +3 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Free living organisms typically occur in harsh environments challenged by abiotic stresses of varying intensities. Taking ionizing radiation and caloric restriction as examples, environmental variation from benign to extreme gives a fitness-stress ...
Peter A. Parsons
doaj +1 more source

