Objective: This trial aimed to identify the Minimum Effective Concentration (MEC90, defined as the concentration which can provide successful block in 90% of patients) of 30 mL ropivacaine for single-shot ultrasound-guided transmuscular Quadratus ...
Jian Hu+3 more
doaj
Exposure/Response vs. Dose/Response Relationships in Drug Development [PDF]
openaire +1 more source
Dasatinib Dose Optimization Based on Therapeutic Drug Monitoring in Patients with Chronic-Phase Chronic Myeloid Leukemia. [PDF]
Cheng F+5 more
europepmc +1 more source
Improving the Dosing Schedules of Targeted Anticancer Agents. [PDF]
Levêque D.
europepmc +1 more source
Comprehensive Safety Exposure-Response Analysis to Support Ritlecitinib Dose Selection. [PDF]
Huh Y+5 more
europepmc +1 more source
Fitness seascapes are necessary for realistic modeling of the evolutionary response to drug therapy. [PDF]
King ES+6 more
europepmc +1 more source
Efficacy and Safety of Olezarsen in Dyslipidemia: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials. [PDF]
Tristan CD+7 more
europepmc +1 more source
A randomized, double-blind, placebo-controlled, Phase 1 study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of an immediate-release oral ketamine capsule in healthy volunteers. [PDF]
Qureshi M+9 more
europepmc +1 more source