Results 241 to 250 of about 1,297,078 (335)

Nitrendipine and Enalapril Combination Therapy in Mild to Moderate Hypertension: Assessment of Dose-Response Relationship by a Clinical Trial of Factorial Design

, 2001
A. Roca-Cusachs, Ferrán Torres, Manuel Horas, José Ríos, Gonzalo Calvo, Joaquim Delgadillo, Maite Terán   +6 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Dose-Response Relationship of Phloretin Therapy on Water and Glucose Transport during Experimental Peritoneal Dialysis. [PDF]

Kidney360
Björk M, Martus G, Öberg CM.
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Oral Artesunate Dose-Response Relationship in Acute Falciparum Malaria

, 2002
Brian Angus, Itaporn Thaiaporn, Kenechanh Chanthapadith, Yupin Suputtamongkol, Nicholas J. White   +4 more
openalex   +1 more source

Exploring the Dose-Response Relationship Between Nature-Based Outdoor Activities, Nature Connectedness and Social Health In Adolescents: A Quasi-Experimental Controlled Study. [PDF]

J Adolesc
Choe EY, Lee JY, Zhu S.
europepmc   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

First evidence of a biomarker-based dose-response relationship in chronic pain using physiological closed-loop spinal cord stimulation. [PDF]

Reg Anesth Pain Med
Muller L, Pope J, Verrills P, Petersen E, Kallewaard JW, Gould I, Karantonis DM.   +6 more
europepmc   +1 more source

Microscale 3D Printed Pillars and Porous Polymeric Structures: Manufacturability and Micromechanics

Advanced Engineering Materials, EarlyView.
This work demonstrates how two‐photon polymerization enables the fabrication of microscale solid and porous structures from IP‐Q, IP‐S, and IP‐PDMS resins. Combining morphological and mechanical characterization, the study provides the first systematic insights into IP‐Q mechanics and reveals how processing parameters affect structure and stiffness ...
Aikaterini Isaakidou, Mahya Ganjian, Vahid Moosabeiki, Marius Alexander Leeflang, Mahdiyeh Nouri Goushki, Pouyan Esmailzadeh Boukany, Maria Wątroba, Alexander Groetsch, Jakob Schwiedrzik, Mohammad Javad Mirzaali, Iulian Apachitei, Lidy Elena Fratila‐Apachitei, Amir Abbas Zadpoor   +12 more
wiley   +1 more source

Latency, Duration and Dose Response Relationships of Amino Acid Effects on Human Muscle Protein Synthesis

, 2002
Michael J. Rennie, Julien Bohé, Robert R. Wolfe   +2 more
openalex   +1 more source