Equilibration of metal metabolism is critical for normal liver function. Most epidemiological studies have only concentrated on the influence of limited metals.
Xu Han+12 more
doaj
Dose-response relationship of treadmill perturbation-based balance training for improving reactive balance in older adults at risk of falling: results of the FEATURE randomized controlled pilot trial. [PDF]
Hezel N+6 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Dose-response relationship and predictive value of soluble B7-DC in bronchoalveolar lavage fluid and risk of refractory Mycoplasma pneumoniae pneumonia in children. [PDF]
Li XH, Xu JM.
europepmc +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Secondhand smoking increased the possibility of hypertension with a significant time and frequency dose-response relationship. [PDF]
Cao S+11 more
europepmc +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Bisoprolol dose–response relationship in patients with congestive heart failure: a subgroup analysis in the cardiac insufficiency bisoprolol study (CIBIS II) [PDF]
Tabassome Simon
openalex +1 more source
Nonlinear dose-response relationship between prognostic nutritional index and short-term outcome in acute ischemic stroke: a prospective cohort study. [PDF]
Wang J+6 more
europepmc +1 more source