Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source
Non-linear dose-response relationship between uterine artery pulsatility index and risk of preeclampsia in early pregnancy: A secondary analysis based on a nested cohort study. [PDF]
Wang S, Dong H.
europepmc +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar+6 more
wiley +1 more source
Dose-response relationship between leisure-time physical activity patterns and phenotypic age acceleration in American adults: A cross-sectional analysis. [PDF]
Wu D+9 more
europepmc +1 more source
Ferroelectricity in Single‐Crystalline BaTiO3 Nanodisks on Silicon
Ferroelectricity is studied in 20 nm thick single crystalline BaTiO3 nanodisks when scaling their diameter from ≈ 400 down to 100 nm. For 100 nm diameter, the vertical polarization component adopts three distinct patterns, and the lateral one shows a rotational invariance in‐plane, suggesting a combination of center‐type and flux‐closure domains.
Ibukun Olaniyan+9 more
wiley +1 more source
Human EWS-FLI protein levels and neomorphic functions show a complex, function-specific dose-response relationship in Drosophila. [PDF]
Mahnoor S+7 more
europepmc +1 more source
Dose-response relationship of serum ferritin and dietary iron intake with metabolic syndrome and non-alcoholic fatty liver disease incidence: a systematic review and meta-analysis. [PDF]
Yu L, Que T, Zhou Y, Liu Z.
europepmc +1 more source
The dose-response relationship between physical activity and the risk of death from pneumonia in middle-aged and older adults: A meta-analysis. [PDF]
Lu S, Shuai Z, Lu Y.
europepmc +1 more source