Results 21 to 30 of about 728,551 (263)

Analysis of the Dose-Response Effects of Physical Activity on Cardiocerebrovascular and All-Cause Mortality in Hypertension

Frontiers in Cardiovascular Medicine, 2022
BackgroundLeisure-time moderate-to-vigorous physical activity (MV-PA) has been consistently regarded as a protective factor to prevent and treat hypertension.
Jun-Peng Xu, Jun-Peng Xu, Rui-Xiang Zeng, Rui-Xiang Zeng, Hai-Ning Lu, Yu-Zhuo Zhang, Yu-Zhuo Zhang, Xiao-Yi Mai, Xiao-Yi Mai, Shuai Mao, Shuai Mao, Min-Zhou Zhang, Min-Zhou Zhang   +12 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Dose-response relationship between lipids and all-cause mortality in the dialysis population: a meta-analysis

BMC Nephrology
Background The use of lipid-lowering drugs in the dialysis population has been controversial and there is no target for the dialysis population. Objectives To elucidate the dose-response relationship between lipids and all-cause mortality in the dialysis
Ye Yao, Jing Xiong, Mi-Yuan Wang
doaj   +1 more source

The relationship between the treatment frequency and efficacy of acupuncture: A scoping review of clinical trials

Complementary Therapies in Medicine
Objective: To consolidate and analyze the existing evidence on the relationship between acupuncture treatment frequency and its clinical efficacy, clarify research status, trends, and core issues, and provide evidence-based insights for optimizing ...
Guodong Li, Xinyu Hu, Jingli Xing, Yiying Wang, Chenlu Wang, Wennan Yu, Jie Lian, Huijuan Cao   +7 more
doaj   +1 more source

Effects of Aerobic and Speed Training Versus Active Control on Repeated Sprint Ability and Measures of Self-confidence and Anxiety in Highly Trained Male Soccer Players

Sports Medicine - Open, 2023
Background While there is ample evidence on the effects of single-mode aerobic and speed training on physical fitness in soccer players, less is known on the combined effects of these exercise regimens on physical and psychological factors.
Walid Selmi, Raouf Hammami, Sofien Kasmi, Sonia Sehli, Haithem Rebai, Michael Duncan, Mokhtar Chtara, Urs Granacher   +7 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Dose-response relationship

Abstract The dose-response relationship is the measurement of the relationship between the dose of a substance administered and its overall effect, the response. Knowledge of the dose-response is a key aspect of a medicine development programme and concepts such as the dose-response curve, effective dose (ED), toxic dose (TD) and ...
Phil Ambery, Adrian Kilcoyne, Daniel O’Connor   +2 more
  +4 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source