Results 291 to 300 of about 1,339,184 (328)
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Dose-Response Relationship in Radiation Leukæmia
Nature, 1959A SIGNIFICANT contribution is achieved by Drs. Armitage, Court Brown and Doll in evaluating some models postulated in assessing the leukaemogenic potency of radiations. Along this line, it appears relevant to discuss some possible interpretations of a linear dose-response, observed over a limited range of leukaemia incidence, as evidenced in the study ...
P, ARMITAGE +3 more
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Dose-response Relationship in Angiotensin Bioassay
Cardiovascular Research, 1968In the albino rat, pressor response to 1–6 ng valine-5-angiotensin II, aspartic β-amide is a function of the logarithmic transformation of the dose of the drug. The latter transformation should be used to delineate dose-response relationship during angiotensin bioassay.
T S, Ing +3 more
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Dose-Response Relationships for Meningioma Radiosurgery
American Journal of Clinical Oncology, 2015Dose-response relationships for meningioma radiosurgery are poorly characterized. We evaluated determinants of local recurrence for meningiomas treated with Gamma Knife radiosurgery (GKRS), to guide future treatment approaches to optimize tumor control.A total of 101 consecutive patients (108 tumors) who underwent GKRS for benign, atypical, or ...
Rajni A, Sethi +9 more
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1987
One of the most powerful tools in the analysis of toxicological events is the description of the intensity of the exposure in terms of dose, dose rate, or concentration for a specified duration of exposure in relation to the frequency or intensity of the observed responses.
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One of the most powerful tools in the analysis of toxicological events is the description of the intensity of the exposure in terms of dose, dose rate, or concentration for a specified duration of exposure in relation to the frequency or intensity of the observed responses.
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2009
In general, the effect of a drug can be considered to be proportional to its dose; the documentation of such a relationship is important in early investigations of drug effects; effects with biological substances as e.g. interferons may go through an optimum, i.e. decreasing with increasing doses; → see also phase i.
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In general, the effect of a drug can be considered to be proportional to its dose; the documentation of such a relationship is important in early investigations of drug effects; effects with biological substances as e.g. interferons may go through an optimum, i.e. decreasing with increasing doses; → see also phase i.
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Dose-Response Relationship With Venlafaxine
Journal of Clinical Psychopharmacology, 1996Considerations when selecting a first-line antidepressant agent include the potential for achieving greater response with increasing dosages, thereby allowing greater flexibility in dosing. The efficacy and dose-response of venlafaxine, a novel serotonin and norepinephrine reuptake inhibitor, was evaluated in two placebo-controlled studies.
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Dose-response relationship in skin sensitization
Food and Chemical Toxicology, 1994The dose-response relationship (challenge phase) of the skin sensitization response was investigated in previously sensitized Hartley guinea pigs. Larger numbers of animals were used per group at the lower doses so that statistically significant observations could be made.
R L, Bronaugh, C D, Roberts, J L, McCoy
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Dose-Response Relationship of Phototherapy for Hyperbilirubinemia
Pediatrics, 2012BACKGROUND AND OBJECTIVE: Using light-emitting diodes during conventional phototherapy, it is possible to reduce the distance from light source to infant, thus increasing light irradiance. The objective of this study was to search for a “saturation point” (ie, an irradiation level above which there is no further
Vandborg, Pernille Kure +3 more
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The Dose-Response Relationship of Tranexamic Acid
Anesthesiology, 1995Background Prophylactic administration of the antifibrinolytic drug tranexamic acid decreases bleeding and transfusions after cardiac operations. However, the best dose of tranexamic acid for this purpose remains unknown. This study explored the dose-response relationship of tranexamic acid for hemostatic efficacy after cardiac
J C, Horrow +4 more
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1985
In this chapter, experimental results concerning the quantitative relationship between the atmospheric concentrations of ozone and PAN and effects on higher plants will be described, documented, and evaluated. The goal is to establish the limits of impact by photochemical oxidants on vegetation as a basis for risk prognosis and to pave the way for ...
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In this chapter, experimental results concerning the quantitative relationship between the atmospheric concentrations of ozone and PAN and effects on higher plants will be described, documented, and evaluated. The goal is to establish the limits of impact by photochemical oxidants on vegetation as a basis for risk prognosis and to pave the way for ...
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