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Nail dystrophy due to dose-intensive chemotherapy
International Journal of Hematology, 2009A 27-year-old male was diagnosed with stage IIB Hodgkin’s lymphoma with bilateral involvement of cervical, supraclavicular and axillary lymph nodes. Additionally, he had a large mediastinal mass ([1/3 of the maximal thoracic diameter) and an elevated erythrocyte sedimentation rate ([30 mm/h) which classified as an advanced stage disease according to ...
M R, Weihrauch +1 more
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Dose-intensive therapy in lung cancer
Cancer Chemotherapy and Pharmacology, 1997Lung cancer is epidemic and lethal throughout the world. Overall survival is estimated to be 13% at 5 years despite treatment. The use of chemotherapy in small-cell lung cancer (SCLC) is established, but it is less active against non-SCLC (NSCLC). Since 98% of SCLC cases are associated with heavy smoking and present at a median age of 60-65 years, the ...
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Exercise Intensity, Dose, and Cardiovascular Disease—Reply
JAMA, 2016Item does not contain ...
Eijsvogels, Thijs M. H. +1 more
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Bulletin du cancer, 1995
The cytotoxic activity of cancer chemotherapy is related to the dose and to the amount of drug delivered per time unit. The significance of time in the effectiveness of a treatment program is frequently overlooked. The term of dose intensity (DI) is used to define the drug dose delivered per time unit and is expressed as mg/m2 per week.
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The cytotoxic activity of cancer chemotherapy is related to the dose and to the amount of drug delivered per time unit. The significance of time in the effectiveness of a treatment program is frequently overlooked. The term of dose intensity (DI) is used to define the drug dose delivered per time unit and is expressed as mg/m2 per week.
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The Tolerance Dose or Tolerance Intensity
Radiology, 1946Radiological Research Laboratory, Columbia University, New York City In view of the serious damage which may result from too much exposure to radiation, it becomes extremely important to determine the amount which can be tolerated without producing any undesirable effects.
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Radiation doses to neonates requiring intensive care
The British Journal of Radiology, 1983Radiological investigations have become accepted as an important part of the range of facilities required to support severely ill newborn babies. Increasing numbers of these very small premature babies now survive although they may undergo a considerable number of diagnostic X-ray examinations within the first few weeks of life.
A, Robinson, H D, Dellagrammaticas
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The Journal of infusional chemotherapy, 1997
The rationale for platinum dose-intensity is based on pharmacologic principles, laboratory observations, and retrospective analysis of clinical studies. However, prospective studies have indicated that dose-intensity studies have been limited by toxicities, restricting the dose increase for cisplatin to approximately twice the conventional dose and for
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The rationale for platinum dose-intensity is based on pharmacologic principles, laboratory observations, and retrospective analysis of clinical studies. However, prospective studies have indicated that dose-intensity studies have been limited by toxicities, restricting the dose increase for cisplatin to approximately twice the conventional dose and for
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2014
This chapter deals essentially with the nonlinear growth of thermoluminescence (TL) intensity with radiation dose. After a brief review of earlier theories and earlier works on this subject, the discussion takes up the so-called heating stage competition model to explain the nonlinear behavior of TL growth with dose.
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This chapter deals essentially with the nonlinear growth of thermoluminescence (TL) intensity with radiation dose. After a brief review of earlier theories and earlier works on this subject, the discussion takes up the so-called heating stage competition model to explain the nonlinear behavior of TL growth with dose.
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Seminars in oncology, 1989
The dose intensity of cisplatin is an important factor in achieving optimal therapeutic results, particularly in ovarian and testicular cancer. Pharmacologic techniques have permitted dose escalation to 200 mg/m2 per cycle. However, further escalations in cisplatin dose are not currently possible due to the development of dose-limiting peripheral ...
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The dose intensity of cisplatin is an important factor in achieving optimal therapeutic results, particularly in ovarian and testicular cancer. Pharmacologic techniques have permitted dose escalation to 200 mg/m2 per cycle. However, further escalations in cisplatin dose are not currently possible due to the development of dose-limiting peripheral ...
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VARIABILITY IN DOSE INTENSITY OF HIGH-DOSE METHOTREXATE FOR NONMETASTATIC OSTEOSARCOMA
Pediatric Hematology and Oncology, 2002The authors evaluated their ability to maintain planned dosing schedules for high-dose methotrexate (HD-MTX) in patients with nonmetastatic osteosarcoma. Twenty-seven patients who received therapy according to 2 POG protocols (8651 and 9351), both of which included HD-MTX (12 g/m(2)/week for 2 consecutive weeks), between 1988 and 1998 were studied ...
Patrick J, Leavey +2 more
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