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Dose modifications and dose intensity during treatment with pirfenidone
1.13 Clinical Problems - Other, 2016Background: During treatment of idiopathic pulmonary fibrosis with pirfenidone (PFD), gastrointestinal and skin-related adverse drug reactions (ADR) occurred in ∼30% of patients (pts). Temporary dose reductions and interruptions may allow pts to better manage side effects and continue PFD. Objective: To evaluate PFD reductions and interruptions in the
Steven Nathan +8 more
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Constant Intensity Image for Minimum Dose Radiography
The British Journal of Radiology, 1958Modern day emphasis on radiation dose minimisation possibly suggests a basic alteration in many diagnostic X-ray procedures. For statistical reasons, in an image one needs a certain minimum number of information carriers per unit area to differentiate structure.
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Dose intensity for breast cancer.
Oncology (Williston Park, N.Y.), 2001Despite nearly 20 years of study, the importance of chemotherapy dose intensity in breast cancer remains unclear. Substantial preclinical data suggest a dose-response relationship, and consistent data document that recipients of substandard dosing have inferior outcomes.
D K, Armstrong, N E, Davidson
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Advanced ovarian cancer. Dose intensity.
Annals of oncology : official journal of the European Society for Medical Oncology, 1994The rationale for dose intensity is based on pre-clinical observations in experimental model systems of cancer as well as upon retrospective studies correlating the impact of dose intensity upon response rates and survival.A review has been performed based on trials attempting to compare the effects of two different dose intensities of either cisplatin
Ozols, R F +7 more
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[Dose intensity in cancer chemotherapy (including high dose chemotherapy)].
Gan to kagaku ryoho. Cancer & chemotherapy, 1995It has been difficult to compare the impact of different dosing practices in treatment programs. Hryniuk and colleagues retrospectively analyzed treatment outcome in a number of different tumors as a function of what they have termed dose intensity.
Y, Ariyoshi, M, Ogawa
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S34 Dose intensity and dose density
European Journal of Cancer, 1998M.J. Piccart, L. Biganzoli, A. Di Leo
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Optimising chemotherapy dose density and dose intensity
European Journal of Cancer, 2000A.M Gianni, M.J Piccart
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