Results 271 to 280 of about 89,922 (309)
Some of the next articles are maybe not open access.
The double-strand-break repair model for recombination
Cell, 1983Gene conversion is the nonreciprocal transfer of information from one DNA duplex to another; in meiosis, it is frequently associated with crossing-over. We review the genetic properties of meiotic recombination and previous models of conversion and crossing-over.
J W, Szostak +3 more
openaire +2 more sources
Processing of DNA Double-Strand Breaks in Yeast
2018Single-stranded DNA (ssDNA) intermediates are essential for homology-dependent repair of DNA double-strand breaks (DSBs) and for the DNA damage response. Here we describe methods routinely used to identify ssDNA intermediates formed by end processing of site-specific DSBs in Saccharomyces cerevisiae.
Robert, Gnügge +2 more
openaire +2 more sources
Nucleosome remodelers in double-strand break repair
Current Opinion in Genetics & Development, 2013ATP-dependent nucleosome remodelers use ATP hydrolysis to shift, evict and exchange histone dimers or octamers and have well-established roles in transcription. Earlier work has suggested a role for nucleosome remodelers such as INO80 in double-strand break (DSB) repair.
Seeber Andrew +2 more
openaire +3 more sources
NF-κB activation by double-strand breaks
Biochemical Pharmacology, 2006Cellular response to DNA damage is complex and relies on the simultaneous activation of different networks. It involves DNA damage recognition, repair, and induction of signalling cascades leading to cell cycle checkpoint activation, apoptosis, and stress related responses. The fate of damaged cells depends on the balance between pro- and antiapoptotic
Yvette, Habraken, Jacques, Piette
openaire +2 more sources
DNA Double-Strand Breaks and their Relation to Cytoxicity
1988In previous publications we have proposed that DNA double strand breaks were the crucial lesions leading to radiation induced cell death, chromosomal aberrations and mutations, and furthermore we have argued that the double strand breaks were induced according to linear-quadratic dose kinetics.
Chadwick, KH +3 more
openaire +2 more sources
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
Molecular Cell, 2021Ruben Schep +2 more
exaly
Mapping the genetic landscape of DNA double-strand break repair
Cell, 2021Jeffrey A Hussmann +2 more
exaly
Reactome - a curated knowledgebase of biological pathways, 2004
S Lees-Miller, L Thompson
openaire +1 more source
S Lees-Miller, L Thompson
openaire +1 more source
The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair
Cell, 2016Julian Lange +2 more
exaly