Results 61 to 70 of about 1,052,978 (300)

Isolation of 10 cyclosporine metabolites from human bile [PDF]

, 1989
Ten metabolites of cyclosporine were isolated from the ethyl ether extract of bile from four liver transplant patients receiving cyclosporine. Two of the metabolites were unique and previously unidentified.
Burckart, GJ, Hartman, NR, Jardine, I, Knapp, JE, Lin, FT, Starzl, TE, Venkataramanan, R, Wang, CP   +7 more
core  

Proline affects the size of the root meristematic zone in Arabidopsis [PDF]

, 2015
We reported previously that root elongation in Arabidopsis is promoted by exogenous proline, raising the possibility that this amino acid may modulate root growth.
BIANCUCCI, MARCO, COSTANTINO, Paolo, MATTIOLI, ROBERTO, MOUBAYIDIN, LAILA, SABATINI, Sabrina, TROVATO, Maurizio   +5 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Outstanding chain-extension effect and high UV resistance of polybutylene succinate containing amino-acid-modified layered double hydroxides

Beilstein Journal of Nanotechnology, 2019
Polybutylene succinate (PBS) nanocomposite materials were prepared using a melt compounding process. The Mg2Al-based PBS nanocomposites, dispersed with inorganic–organic hybrid materials (layered double hydroxides, LDHs), were functionalized with the ...
Adam A. Marek, Vincent Verney, Christine Taviot-Gueho, Grazia Totaro, Laura Sisti, Annamaria Celli, Fabrice Leroux   +6 more
doaj   +1 more source

ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming

Open Biology, 2022
MreB is a bacterial protein belonging to the actin superfamily. This protein polymerizes into an antiparallel double-stranded filament that determines cell shape by maintaining cell wall synthesis.
Daichi Takahashi, Ikuko Fujiwara, Yuya Sasajima, Akihiro Narita, Katsumi Imada, Makoto Miyata   +5 more
doaj   +1 more source

Green Production of Anionic Surfactant Obtained from Pea Protein [PDF]

, 2011
A pea protein isolate was hydrolyzed by a double enzyme treatment method in order to obtain short peptide sequences used as raw materials to produce lipopeptides-based surfactants.
A Clemente, A Tsoukala, A Villanueva, AF Dexter, Bénédicte Portet, C Megias, C Rondel, Caroline Rondel, CN Mulligan, D Kitamoto, EA Pena-Ramos, FM Netto, Françoise Silvestre, H Frister, H Schägger, Isabelle Alric, J Vioque, Jean-François Blanco, JS Hamada, JY Lee, K Pommer, K Yasamatsu, LA Graaf De, LM Humiski, M Dall Aaslyng, M Karamac, M Le Gall, MC Marquez, MPC Silvestre, MR Infante, P Anastas, PM Nielsen, R Amarowicz, R Sanchez-Vioque, R Sanchez-Vioque, R Sinha, RT Swank, S Jung, TS Padmashree, UK Laemmli, Zéphirin Mouloungui   +40 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The role of amino acid metabolism alterations in acute ischemic stroke: From mechanism to application

Pharmacological Research
Acute ischemic stroke (AIS) is the most prevalent type of stroke, and due to its high incidence, disability rate, and mortality rate, it imposes a significant burden on the health care system.
Xiang-Ping Wang, Dan Yan, Xia-Ping Jin, Wen-Yan Zhang, Tao Shi, Xiang Wang, Wenjuan Song, Xing Xiong, Duancheng Guo, Sheng Chen   +9 more
doaj   +1 more source

Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]

, 1990
We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M., Strauss, James H.   +1 more
core