Results 81 to 90 of about 1,047,229 (199)

Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvation

open access: yesGenome Biology
Background Cells regulate protein synthesis in response to fluctuating nutrient availability through mechanisms that affect both translation initiation and elongation.
Lina Worpenberg   +2 more
doaj   +1 more source

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]

open access: yes, 1992
To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD   +6 more
core  

Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away

open access: yes, 2013
Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms.
Forsdyke, Donald R.
core   +1 more source

Role of symbiotic auxotrophy in the Rhizobium-legume symbioses.

open access: yesPLoS ONE, 2010
BackgroundRhizobium leguminosarum bv. viciae mutants unable to transport branched-chain amino acids via the two main amino acid ABC transport complexes AapJQMP and BraDEFGC produce a nitrogen starvation phenotype when inoculated on pea (Pisum sativum ...
Jurgen Prell   +7 more
doaj   +1 more source

Isolation of 10 cyclosporine metabolites from human bile [PDF]

open access: yes, 1989
Ten metabolites of cyclosporine were isolated from the ethyl ether extract of bile from four liver transplant patients receiving cyclosporine. Two of the metabolites were unique and previously unidentified.
Burckart, GJ   +7 more
core  

Mutant and chimeric recobinant plasminogen activatorsproduction in eukaryotic cellsand preliminary characterization [PDF]

open access: yes, 1987
Mutant urokinase-type plasminogen activator (u-PA) genes and hybrid genes between tissue-type plasminogen activator (t-PA) and u-PA have been designed to direct the synthesis of new plasminogen activators and to investigate the structure-function ...
Andre, B.   +11 more
core   +1 more source

A novel family of (1-aminoalkyl)(trifluoromethyl)- and -(difluoromethyl)phosphinic acids – analogues of α-amino acids

open access: yesBeilstein Journal of Organic Chemistry, 2014
A series of novel (1-aminoalkyl)(trifluoromethyl)- and -(difluoromethyl)phosphinic acids – analogues of proteinogenic and nonproteinogenic α-amino acids were prepared.
Natalia V. Pavlenko   +5 more
doaj   +1 more source

N-Substituted unusual amino acids as corrosion inhibitors. Part IV: N-Acyl derivatives of unnatural amino acids with double bond

open access: yesInternational Journal of Corrosion and Scale Inhibition, 2016
Corrosion inhibition efficiency of unusual phenyl alanine derivatives (substituted in the phenyl ring and double bond in the side chain) were investigated in neutral aqueous solution by weight loss test and by atomic force microscopy. The influence of the substituents in the phenyl ring as well as of the double bond was elucidated and explained.
openaire   +1 more source

Uncharged tRNA Activates GCN2 by Displacing the Protein Kinase Moiety from a Bipartite tRNA-Binding Domain [PDF]

open access: yes, 2000
Protein kinase GCN2 regulates translation in amino acid–starved cells by phosphorylating eIF2. GCN2 contains a regulatory domain related to histidyl-tRNA synthetase (HisRS) postulated to bind multiple deacylated tRNAs as a general sensor of starvation ...
Anderson, James T.   +4 more
core   +1 more source

Carbon--The First Frontier of Information Processing [PDF]

open access: yes, 2001
Information is often encoded as an aperiodic chain of building blocks. Modern digital computers use bits as the building blocks, but in general the choice of building blocks depends on the nature of the information to be encoded.
Patel, Apoorva
core   +1 more source

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