Results 41 to 50 of about 1,701,712 (263)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Jus in bello a operace Irácká svoboda
Obrana a Strategie, 2010 War is a constant feature of human affairs and a permanent topic of ethical debates. Moral reasoning about war and peace known as just war theory has its roots in Christian ethics and is connected to positive international law.
Eva DUŘPEKTOVÁ, Zdeněk KŘÍŽ
doaj
Nonresponse Effect in Double Sampling: A Simulation Study [PDF]
The Egyptian Statistical Journal, 1995 We consider estimation of the population total in double sampling for regression in the presence of nonresponse. Two estimators were examined, one allowing for nonresponse and the other based only on respondents'set.
Mohamad Hasan, Z. EL-Beshir
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Evolution of correlated electrons in La3Ni2O7 at ambient pressure: a study of double-counting effect
AAPPS BulletinWe employ cluster extension of dynamical mean-field theory (CDMFT) to systematically investigate the impact of double counting corrections on the correlated electronic structure of La3Ni2O7 under ambient pressure. By adjusting double-counting parameters,
Zhongyi Xie +3 more
doaj +1 more source
The Double-Edged Effects of MLN4924: Rethinking Anti-Cancer Drugs Targeting the Neddylation Pathway
Biomolecules(1) Background: The neddylation pathway assumes a pivotal role in the initiation and progression of cancer. MLN4924, a potent small-molecule inhibitor of the NEDD8-activating enzyme (NAE), effectively intervenes in the early stages of the neddylation ...
Haoming Tang +3 more
doaj +1 more source
Shuiwen dizhi gongcheng dizhi, 2022 As a new type of cantilever-type supporting structure, the double-row pile supporting combination system can improve the overall rigidity to maintain the safety and stability of the side of the foundation pit. The case of a double-row pile foundation pit
Fengwu GONG +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Simulation Study on Solar Single/Double-Effect Switching LiBr-H2O Absorption Refrigeration System
Energies, 2023 In this study, a solar single/double-effect switching LiBr-H2O absorption refrigeration system was investigated to make full use of solar energy and give full play to the advantages of solar refrigeration systems.
Qingyang Li +6 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source