Results 41 to 50 of about 129,616 (305)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Excitability in a quantum dot semiconductor laser with optical injection [PDF]

open access: yes, 2007
We experimentally analyze the dynamics of a quantum dot semiconductor laser operating under optical injection. We observe the appearance of single- and double-pulse excitability at one boundary of the locking region.
Goulding, David   +8 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Hot electron electrochemistry at silver activated by femtosecond laser pulses

open access: yesOpto-Electronic Advances, 2023
A silver microelectrode with a diameter of 30 µm in an aqueous K2SO4 electrolyte was irradiated with 55 fs and 213 fs laser pulses. This caused the emission of electrons which transiently charged the electrochemical double layer.
Oskar Armbruster   +2 more
doaj   +1 more source

Restricted space ab initio models for double ionization by strong laser pulses

open access: yes, 2018
Double electron ionisation process occurs when an intense laser pulse interacts with atoms or molecules. Exact {\it ab initio} numerical simulation of such a situation is extremely computer resources demanding, thus often one is forced to apply reduced ...
Chacón, Alexis   +7 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Coherent, Short-Pulse X-ray Generation via Relativistic Flying Mirrors

open access: yesQuantum Beam Science, 2018
Coherent, Short X-ray pulses are demanded in material science and biology for the study of micro-structures. Currently, large-sized free-electron lasers are used; however, the available beam lines are limited because of the large construction cost.
Masaki Kando   +4 more
doaj   +1 more source

Classical Effects of Laser Pulse Duration on Strong-field Double Ionization

open access: yes, 2005
We use classical electron ensembles and the aligned-electron approximation to examine the effect of laser pulse duration on the dynamics of strong-field double ionization.
A. M. Perelomov   +7 more
core   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar   +6 more
wiley   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat   +5 more
wiley   +1 more source

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