Results 71 to 80 of about 79,920 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Exploring companies' relationships with environmental indicators from the European sustainability reporting standards (ESRS) – The case of NorwayMendeley Data

Current Research in Environmental Sustainability
The Corporate Sustainability Reporting Directive (CSRD) marks a major shift in EU sustainability reporting by requiring compliance with the European Sustainability Reporting Standards (ESRS). This study examines how a sample of Norwegian companies relate
Jørgen Kjøsen Lindgren, Adrian Tobias Werner, Nora Johanne Klungseth, Bjørn Sørskot Andersen   +3 more
doaj   +1 more source

The wood: Cover of the art and metaphor of the return from 1968

Anales de Historia del Arte, 2013
The landscape genre resurfaced with renewed forces beginning in the sixties of the twentieth century through the land art and the earthworks. The pioneers Americans felt a special love for the desert and the places which are difficult to access by ...
Ana Esther Santamaría Fernández
doaj   +1 more source

Language, Subjectivity and Individuality [PDF]

, 2007
It is clear that within Deleuze and Whitehead’s work, there is an important re- description of the time, place and status of all subjectivity, a subjectivity which is not limited to the ‘human’. Both writers provide compelling reasons as to why, and how,
Halewood, Michael
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Real effects of greenhouse gas disclosures

China Journal of Accounting Research
This study investigates the valuation and real effects of the mandatory disclosure of greenhouse gas (GHG) emission costs from the perspective of “double materiality.” We consider a firm with a Cobb-Douglas production function that combines GHG-related ...
Tong Lu, Lijun Ruan, Yanyan Wang, Lisheng Yu   +3 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The production of maquiladora space in Motul, Mexico: from henequen municipality to industrial city

Articulo: Journal of Urban Research, 2020
At the intersection of commodity chains and urban research, this paper engages with Bair and Werner’s “disarticulations perspective” through a conversation with Lefebvre’s “production of space.” I argue that this mix can provide a stronger theoretical ...
Claudia Fonseca Alfaro
doaj   +1 more source