Results 81 to 90 of about 79,920 (305)
The Remanence of Medieval Media [PDF]
, 2017 The Remanence of Medieval Media (uncorrected, pre-publication version) For: The Routledge Handbook of Digital Medieval Literature, edited by Jen Boyle and Helen Burgess ...
Martin Foys
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
, 2004 In the course of this talk, I want to try and address one main question: what is architecture? Implicit within this are also some reflections on what or who is an architectural historian or commentator?
Borden, Iain
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
10 Double Bind: On Material Ethics
, 2021 The chapter champions the neologism ethico-aesthetic in order to underline the inseparability of action and perception. The chapter argues that it is practice and experimentation that actively shape the subject. Until recently the sentient was considered as a mere supplement to the sapient.
openaire +2 more sources
Valuing service design: Lessons from SROI [PDF]
, 2012 This paper describes lessons learned through the use of a Social Return On Investment (SROI) approach to evaluate a completed Service Design project with a large vocational training company.
Lievesley, Matthew, Yee, Joyce
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SOME REFLECTIONS ON DOUBLE NEGATIVE MATERIALS [PDF]
Progress In Electromagnetics Research, 2005 We study the energy conservation property and loss condition of a left-handed material (LHM). First we argue by energy conservation that an LHM has to be a backward-wave material (BWM). Then we derive the equivalence of the loss and the Sommerfeld far-field radiation conditions for BWM.
openaire +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Harsh Poetry and Art's Address: Romare Bearden and Hans-Georg Gadamer in Conversation [PDF]
, 2016 In this essay, I analyze Romare Bearden’s art, methodology, and thinking about art, as well as his attempt to harmonize his personal aesthetic goals with his sociopolitical concerns.
Nielsen, Cynthia R.
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source