Results 81 to 90 of about 213,326 (261)

Fast Proxy Centers for the Jeffreys Centroid: The Jeffreys–Fisher–Rao Center and the Gauss–Bregman Inductive Center

open access: yesEntropy
The symmetric Kullback–Leibler centroid, also called the Jeffreys centroid, of a set of mutually absolutely continuous probability distributions on a measure space provides a notion of centrality which has proven useful in many tasks, including ...
Frank Nielsen
doaj   +1 more source

Posttraining Alpha Transcranial Alternating Current Stimulation Impairs Motor Consolidation in Elderly People

open access: yesNeural Plasticity, 2019
The retention of a new sequential motor skill relies on repeated practice and subsequent consolidation in the absence of active skill practice. While the early phase of skill acquisition remains relatively unaffected in older adults, posttraining ...
Jost-Julian Rumpf   +4 more
doaj   +1 more source

I_2-Cesàro summability of double sequences of sets

open access: yes, 2015
In this paper, we de ned concept of Wijsman I2-Cesàro summability and investigate the relationship between the concepts of Wijsman strongly I2-Cesàro summability, Wijsman strongly I2-lacunary convergence, Wijsman p-strongly I2-Cesàro summability and Wijsman I2-statistical convergence of double sequences of sets.
Ulusu, Uğur   +2 more
openaire   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Generating information-dense promoter sequences with optimal string packing.

open access: yesPLoS Computational Biology
Dense arrangements of binding sites within nucleotide sequences can collectively influence downstream transcription rates or initiate biomolecular interactions.
Virgile Andreani   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Occurrence of Thermotolerant Hartmannella Vermiformis and Naegleria Spp. in Hot Springs of Ardebil Province, Northwest Iran [PDF]

open access: yesIranian Journal of Parasitology, 2012
Background: Geothermal waters could be suitable niches for thermophilic free living amoebae including Naegleria and Hartmannella. Ardebil Province, northwest Iran is popular for having many hot springs for recreational and health purposes activity.
E Nazemalhosseini Mojarad   +3 more
doaj   +2 more sources

Facial Expression Recognition From Image Sequence Based on LBP and Taylor Expansion

open access: yesIEEE Access, 2017
The aim of an automatic video-based facial expression recognition system is to detect and classify human facial expressions from image sequence. An integrated automatic system often involves two components: 1) peak expression frame detection and 2 ...
Yuanyuan Ding   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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