Results 41 to 50 of about 1,374,973 (285)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A new double series space derived by factorable matrix and four-dimensional matrix transformations

AIMS Mathematics
In this study, we introduce a new double series space $ \left\vert F_{a, b}^{u, \theta }\right\vert _{k} $ using the four dimensional factorable matrix $ F $ and absolute summability method for $ k\geq 1 $.
Aslıhan ILIKKAN CEYLAN , Canan HAZAR GÜLEÇ   +1 more
doaj   +1 more source

$\mathcal{I}_2$-Uniform Convergence of Double Sequences of Functions In $2$-Normed Spaces

Communications in Advanced Mathematical Sciences, 2022
In this work, we discuss various types of $\mathcal{I}_2$-uniform convergence and equi-continuous for double sequences of functions. Also, we introduce the concepts of $\mathcal{I}_2$-uniform convergence, $\mathcal{I}_2^*$-uniform convergence, $\mathcal ...
Mukaddes Arslan, Sevim Yegül Güzey, Erdinç Dündar   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Korovkin-Type Approximation Theorems for Statistical Gauge Integrable Functions of Two Variables

Stats
In this work, we develop and investigate statistical extensions of gauge integrability and gauge summability for double sequences of functions of two real variables, formulated within the framework of deferred weighted means.
Hari Mohan Srivastava, Bidu Bhusan Jena, Susanta Kumar Paikray, Umakanta Misra   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

On deferred f-statistical convergence for double sequences

Open Mathematics
In this article, we first put forward the concept of deferred f-double natural density for double sequences, where f is an unbounded modulus. Then, we combine f-density with deferred statistical convergence for double sequences and investigate deferred f-
Zhu Yahui, Shen Ang, Wang Zhongzhi, Peng Weicai   +3 more
doaj   +1 more source

Frames generated by double sequences in Hilbert spaces [PDF]

Mathematica Moravica, 2023
In this paper, we introduce frames generated by double sequences (d-frame) in Hilbert spaces and describe some of their properties. Furthermore, we discuss frame operators, alternate dual frames and stability for d-frames.
Biswas Narendra, Mehra Chetna, Joshi Mahesh C.   +2 more
doaj  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source