Results 81 to 90 of about 1,889,311 (309)
Double-blind peer review and gender publication bias [PDF]
, 2008 Engqvist L, Frommen JG. Double-blind peer review and gender publication bias. Animal Behaviour.
Frommen, Joachim G +1 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Optimal designs for estimating the slope of a regression [PDF]
In the common linear regression model we consider the problem of designing experiments for estimating the slope of the expected response in a regression.
Dette, Holger, Melas, Viatcheslav B.
core
Numerical analysis of deformation in the upper part of subduction zones [PDF]
, 1981 The stresses and deformation in an accretionary prism, and the crystalline basement behind and beneath it, have been modelled using finite element analysis, assuming a visco-elastic Maxwell rheology for the rocks involved.
Park, M.J.M.
core
Single, double and surround gate vertical MOSFETs with reduced parasitic capacitance [PDF]
, 2004 The vertical MOSFET structure is one of the solutions for reducing the channel length of transistors under 50nm. Surround gates can be easily realised in vertical MOSFETs which offer increased channel width per unit silicon area.
Wang, Y +17 more
core +1 more source
Stability analysis of ultra-high and steep reinforced soil fills slopes based on strength reduction [PDF]
Archives of Civil EngineeringThe research focuses on solving the important problem of slope stability in the field of civil engineering. The study adopted an advanced strength double reduction coefficient method for slope stability analysis, which considers the different influence ...
Yucong Gao +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Analysis on the response of the dip slope with weak layer to earthquake
Zhongguo dizhi zaihai yu fangzhi xuebaoTaking the down-slope with weak strata in the south of Fushun west open-pit mine as the reference prototype, numerical simulations of the down-slope with weak strata were conducted through FLAC3D software, which included the simulation of actual ground ...
Laigui WANG +3 more
doaj +1 more source