Results 1 to 10 of about 6,000 (194)

Doublesex and GATAβ4 synergistically regulate the sex-dimorphic expression of storage protein 1 in Bombyx mori. [PDF]

PLoS Genet
Sexually dimorphic traits are widespread in organisms and are crucial for reproduction and behavior. These traits are typically controlled by sex-specific genes. However, their regulatory mechanisms are complex and incompletely understood. In Bombyx mori,
Yan J, Dong H, Tian T, Xiao C, Sun Y, Gong J, Xia Q, Hou Y.   +7 more
europepmc   +2 more sources

Genomic analyses revealed low genetic variation in the intron-exon boundary of the doublesex gene within the natural populations of An. gambiae s.l. in Burkina Faso. [PDF]

BMC Genomics
Background The recent success of a population control gene drive targeting the doublesex gene in Anopheles gambiae paved the way for developing self-sustaining and self-limiting genetic control strategies targeting the sex determination pathway to reduce
Kientega M, Morianou I, Traoré N, Kranjc N, Kaboré H, Zongo ON, Millogo AA, Epopa PS, Yao FA, Belem AMG, Burt A, Diabaté A.   +11 more
europepmc   +3 more sources

Tissue-specific metabolomic signatures for a <i>doublesex</i> model of reduced sexual dimorphism. [PDF]

R Soc Open Sci
Sex has a major effect on the metabolome. However, we do not yet understand the degree to which differences in metabolism are associated with anatomical dimorphism and modulated by sex-specific tissues. In the fruit fly, Drosophila melanogaster, knocking
Coig R, Harrison B, Johnson R, MacCoss MJ, Promislow D.   +4 more
europepmc   +2 more sources

Establishing a dominant early larval sex-selection strain in the Asian malaria vector Anopheles stephensi. [PDF]

Infect Dis Poverty
Background Genetic biocontrol interventions targeting mosquito-borne diseases require the release of male mosquitoes exclusively, as only females consume blood and transmit pathogens.
Weng SC, Chen F, Li M, Lee S, Gerry C, Turksoy DC, Akbari OS.   +6 more
europepmc   +2 more sources

The Masc-PSI complex directly induces male-type doublesex splicing in silkworms. [PDF]

Commun Biol
The WZ sex determination system is found in a diverse range of animals, including lepidopteran insects. In the silkworm Bombyx mori, the masculinizing protein Masculinizer (BmMasc) induces the production of the male-type Bombyx mori doublesex (Bmdsx M ),
Kaneda T, Matsuda-Imai N, Kosako H, Shoji K, Suzuki MG, Suzuki Y, Kiuchi T, Katsuma S.   +7 more
europepmc   +2 more sources

Candidate target genes of the male-specific expressed Doublesex in the termite Reticulitermes speratus. [PDF]

PLoS One
Eusocial insects such as termites, ants, bees, and wasps exhibit a reproductive division of labor. The developmental regulation of reproductive organ (ovaries and testes) is crucial for distinguishing between reproductive and sterile castes.
Fujiwara K, Miyazaki S, Maekawa K.
europepmc   +2 more sources

DMRT Transcription Factors in the Control of Nervous System Sexual Differentiation

Frontiers in Neuroanatomy, 2022
Sexual phenotypic differences in the nervous system are one of the most prevalent features across the animal kingdom. The molecular mechanisms responsible for sexual dimorphism throughout metazoan nervous systems are extremely diverse, ranging from ...
Rafael Casado-Navarro, Esther Serrano-Saiz   +1 more
doaj   +1 more source

Prokaryotic Expression of Doublesex Gene From Macrobrachium rosenbergii and Protein Purification

Guangdong nongye kexue, 2023
【Objective】Doublesex, a member of the DMRT gene family, plays a key role in controlling sex-specific differentiation. To clone the Open Reading Frame (ORF) of Macrobrachium rosenbergii Doublesex (MrDsx) gene, construct the recombinant plasmid and induce ...
Ruirui WANG, Keyi MA
doaj   +1 more source

Molecular and cellular origins of behavioral sex differences: a tiny little fly tells a lot

Frontiers in Molecular Neuroscience, 2023
Behavioral sex differences primarily derive from the sexually dimorphic organization of neural circuits that direct the behavior. In Drosophila melanogaster, the sex-determination genes fruitless (fru) and doublesex (dsx) play pivotal roles in producing ...
Kosei Sato, Daisuke Yamamoto
doaj   +1 more source

Layered roles of fruitless isoforms in specification and function of male aggression-promoting neurons in Drosophila

eLife, 2020
Inter-male aggressive behavior is a prominent sexually dimorphic behavior. Neural circuits that underlie aggressive behavior are therefore likely under the control of sex-determining genes.
Margot Wohl, Kenichi Ishii, Kenta Asahina   +2 more
doaj   +1 more source