doublesex functions early and late in gustatory sense organ development. [PDF]
PLoS ONE, 2012 Somatic sexual dimorphisms outside of the nervous system in Drosophila melanogaster are largely controlled by the male- and female-specific Doublesex transcription factors (DSX(M) and DSX(F), respectively).
David J Mellert +2 more
doaj +4 more sources
Fruitless, Doublesex And The Genetics Of Social Behavior In Drosophila Melanogaster [PDF]
Current Opinion in Neurobiology, 2009 Two genes coding for transcription factors, fruitless and doublesex, have been suggested to play important roles in the regulation of sexually dimorphic patterns of social behavior in Drosophila melanogaster.
Kravitz, E. A., Siwicki, Kathleen King
core +6 more sources
Evolution of sex-specific traits through changes in HOX-dependent doublesex expression. [PDF]
PLoS Biology, 2011 Almost every animal lineage is characterized by unique sex-specific traits, implying that such traits are gained and lost frequently in evolution. However, the genetic mechanisms responsible for these changes are not understood.
Kohtaro Tanaka +4 more
doaj +4 more sources
Feminizer and doublesex knock-outs cause honey bees to switch sexes.
PLoS Biology, 2019 Honey bees are experts at refuting societal norms. Their matriarchal hives are headed by queens, backed by an all-female workforce, and males die soon after copulation.
Alison McAfee +3 more
doaj +3 more sources
Sex-Specific doublesex Regulation Targeting the Color-Patterning Gene h Underlies the Evolution of Wing Sexual Dimorphism in the Harlequin Ladybug Harmonia axyridis. [PDF]
Evol Devdoublesex regulates sexual dimorphism in elytral color patterns of Harmonia axyridis by downregulating the color patterning gene h in males. This regulatory link diverged in derived color morphs, coinciding with the loss of sex‐specific elytral color patterns.
Yeki S +7 more
europepmc +2 more sources
Batesian mimicry has evolved with deleterious effects of the pleiotropic gene doublesex [PDF]
Scientific Reports, 2020 Dimorphic female-limited Batesian mimicry in the swallowtail butterfly Papilio polytes is regulated by the supergene locus H, harbouring the mimetic (H) and non-mimetic (h) doublesex (dsx) gene. In the present study, we demonstrated that dsx-H negatively
Shinya Komata +2 more
doaj +3 more sources
The ubiquity and ancestry of insect doublesex [PDF]
Scientific Reports, 2015 AbstractThe doublesex (dsx) gene functions as a molecular switch at the base of the insect sex determination cascade and triggers male or female somatic sexual differentiation in Drosophila. Having been reported from only seven current insect orders, the exact phylogenetic distribution of dsx within the largest Arthropod sub-phylum, the Hexapoda, is ...
Dana C. Price +2 more
+8 more sources
Constraints on the evolution of adoublesextarget gene arising from doublesex’s pleiotropic deployment [PDF]
Proceedings of the National Academy of Sciences, 2015 SignificanceMost sexually dimorphic features ofDrosophila melanogasterare specified by the action of sex-specific transcription factors encoded by thedoublesex(dsx) gene. Evolutionary changes in such sexually dimorphic features are often a result of changes in thecis-regulatory sequences of the DSX target genes.
Shengzhan D, Luo, Bruce S, Baker
openaire +2 more sources
Courtship Love Songs: doublesex Makes the Connection [PDF]
Developmental Cell, 2016 During courtship, Drosophila melanogaster males sing to females a song composed of rhythmic pulses and sine song. In this issue of Developmental Cell, Shirangi et al. (2016) show that a cluster of doublesex-expressing neurons directs the production of the sine song component through functional linkages to wing motoneurons.
Michelle N, Arbeitman, Nicole R, Newell
openaire +2 more sources
Transgenic and knockout analyses of Masculinizer and doublesex illuminated the unique functions of doublesex in germ cell sexual development of the silkworm, Bombyx mori [PDF]
BMC Developmental Biology, 2020 Abstract Background: Masculinizer (Masc) plays a pivotal role in male sex determination in the silkworm, Bombyx mori. Masc is required for male-specific splicing of B. mori doublesex (Bmdsx) transcripts. The male isoform of Bmdsx (BmdsxM) induces male differentiation in somatic cells, while females express the female isoform of Bmdsx (BmdsxF ...
Yuzawa, Tomohisa +5 more
openaire +2 more sources