Results 21 to 30 of about 6,000 (194)

Flipping the doublesex switch with a piRNA [PDF]

open access: yesGenome Biology, 2014
Recent work in the silkworm Bombyx mori has uncovered a novel Piwi-interacting RNA regulator of the sex determination switch doublesex.
Whitworth, Cale, Oliver, Brian
openaire   +2 more sources

Double nexus--Doublesex is the connecting element in sex determination [PDF]

open access: yesBriefings in Functional Genomics, 2015
In recent years, our knowledge of the conserved master-switch gene doublesex (dsx) and its function in regulating the development of dimorphic traits in insects has deepened considerably. Here, a comprehensive overview is given on the properties of the male- and female-specific dsx transcripts yielding DSX(F) and DSX(M) proteins in Drosophila ...
Verhulst, E.C., van de Zande, L.
openaire   +3 more sources

Doublesex target genes in the red flour beetle, Tribolium castaneum [PDF]

open access: yesScientific Reports, 2012
Sex determination cascade in insects terminates with the production of sex-specific protein, Doublesex (Dsx). We identified the dsx homolog (Tcdsx) in Tribolium castaneum. The pre-mRNA of Tcdsx is sex-specifically spliced into three female (Tcdsxf1, Tcdsxf2 and Tcdsxf3) and one male-specific (Tcdsxm) isoforms.
Shukla, Jayendra Nath   +1 more
openaire   +2 more sources

Sex-determining genes distinctly regulate courtship capability and target preference via sexually dimorphic neurons

open access: yeseLife, 2020
For successful mating, a male animal must execute effective courtship behaviors toward a receptive target sex, which is female. Whether the courtship execution capability and upregulation of courtship toward females are specified through separable sex ...
Kenichi Ishii   +3 more
doaj   +1 more source

A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex [PDF]

open access: yes, 2003
The multiprotein Mediator complex is a coactivator required for transcriptional activation of RNA polymerase II transcribed genes by DNA binding transcription factors.
Banks, Charles A. S.   +7 more
core   +1 more source

The Sex-Specific Splicing of Doublesex in Brine Shrimp Artemia franciscana

open access: yesGenes, 2022
The understanding of sex determination and differentiation in animals has recently made remarkable strides through the use of advanced research tools. At the gene level, the Mab-3-related transcription factor (Dmrt) gene family, which encodes for the typical DNA-binding doublesex/Mab-3 (DM) domain in their protein, is known for its contribution to sex ...
Dung Nguyen Viet   +4 more
openaire   +3 more sources

A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms

open access: yesCommunications Biology, 2022
An ancestral male-specific doublesex isoform, dsxM2, is identified via intron retention, with a masculinizing function weaker than the modern ...
Caihong Han   +5 more
doaj   +1 more source

A deep insight into the sialome of male and female aedes aegypti mosquitoes [PDF]

open access: yes, 2016
Only adult female mosquitoes feed on blood, while both genders take sugar meals. Accordingly, several compounds associated with blood feeding (i.e. vasodilators, anti-clotting, anti-platelets) are found only in female glands, while enzymes associated ...
ARCA', Bruno   +3 more
core   +4 more sources

Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females

open access: yesParasites & Vectors, 2019
Background Mosquito-borne diseases affect millions worldwide, with malaria alone killing over 400 thousand people per year and affecting hundreds of millions.
Mabel L. Taracena   +4 more
doaj   +1 more source

Non-coding changes cause sex-specific wing size differences between closely related species of Nasonia. [PDF]

open access: yesPLoS Genetics, 2010
The genetic basis of morphological differences among species is still poorly understood. We investigated the genetic basis of sex-specific differences in wing size between two closely related species of Nasonia by positional cloning a major male-specific
David W Loehlin   +10 more
doaj   +1 more source

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