Results 91 to 100 of about 4,698,937 (316)
, 2012 Los objetivos de la Red Nacional de Hermanos de personas con síndrome de Down, recogidos en su manifiesto de creación son los que se exponen a continuación: crear vínculos entre hermanos de personas con síndrome de Down; los hermanos como plataforma de ...
Down España
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Down-regulation of myogenin can reverse terminal muscle cell differentiation.
PLoS ONE, 2012 Certain higher vertebrates developed the ability to reverse muscle cell differentiation (dedifferentiation) as an additional mechanism to regenerate muscle. Mammals, on the other hand, show limited ability to reverse muscle cell differentiation. Myogenic
Nikolaos P Mastroyiannopoulos +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 1990 Se encuentra un segundo vídeo con otras conferencias de las jornadasEn este vídeo pueden encontrarse las siguientes conferencias : 'La patogenia del retraso mental en la trisomía 21', 'Socialización y sexualidad en personas con síndrome de Down ...
Fundació Catalana Síndrome de Down
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Editorial: Altered Expression of Proteins in Cancer: Function and Potential Therapeutic Targets
Frontiers in Oncology, 2022 João Pessoa +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments
Frontiers in Physiology, 2012 Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source