Results 101 to 110 of about 4,698,937 (316)
Guía de empleo con apoyo para familias con hijos trabajadores [PDF]
, 2013 La metodología del empleo con apoyo se ha confirmado desde hace varios años como una de las grandes herramientas utilizadas para facilitar la inserción laboral de las personas con síndrome de Down en España.
Down España
core
Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes [PDF]
, 2007 Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process.
Jones, Jon +15 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Methodological Appendix for: In Search of the Public Interest
, 2023 This page contains the methodological appendix for "In Search of the Public Interest" by Jodi L. Short, published in the Yale Journal on Regulation (2023)
Yale Journal on Regulation
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sexualidad, afectividad y síndrome de Down: (I) Se hace camino al andar [PDF]
, 2012 Se presentan algunas de las preocupaciones con las que suelen encontrarse las familias y los profesionales en torno a la educación de la sexualidad y afectividad de las personas con síndrome de ...
García, José Luis
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Mis primeros pasos hacia la autonomía [PDF]
, 2013 Guía para fomentar la autonomía de los niños con síndrome de Down desde los primeros años. La publicación está orientada a familias y pretende ayudarles a reconocer la importancia de esta primera etapa, unos años que sentarán, no sólo las bases para su ...
Down España
core
, 2019 Hepatocyte proliferation could result in the loss of covalently closed circular DNA (cccDNA) and the emergence of cccDNA-cleared nascent hepatocytes, which appear refractory to hepatitis B virus (HBV) reinfection with unknown mechanism(s).
Lena Allweiss (366520) +14 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source