Results 61 to 70 of about 1,209,458 (341)

The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway [PDF]

, 2008
Non-melanoma skin cancer is the most frequent malignancy in Caucasian populations. Evidence suggests the involvement of cutaneous Human Papillomavirus (HPV) of the genus beta () in this disease. The ability of E6 and E7 of mucosal HPV to promote cellular
Akgul, Asgari, Ashrafi, Ashrafi, Astori, Barnard, Boxman, Caldeira, Caldeira, Chang, Chatterjee-Kishore, Chen, Cromme, de Villiers, Dong, Friedrich, Gabet, Georgopoulos, Goodbourn, Harwood, Haspel, Hazard, Hughes, IARC Monographs, Ivanov, Jablonska, Jong-Tieben, Kroger, Lawrence Banks, Li, Livak, M. Saveria Campo, Mantovani, Massimi, Massimo Tommasino, Nees, O'Brien, Ohmori, Pablo Cordano, Park, Pear, Perea, Proffitt, Ronco, Sigrid Bratlie, Tang, Veronique Bouvard, Victoria Gillan, Wang, White, Wright   +50 more
core   +1 more source

Osteopontin is down-regulated in hydatidiform mole

Gynecologic Oncology, 2003
Osteopontin (OPN) is a glycoprotein of the extracellular matrix that can bind to different types of receptors including integrins and CD44 receptors. Multiple binding affinity enables OPN to play a role in many physiological and pathological processes. OPN contributes to tumorigenesis in several types of cancers.
Samuel C. Mok, József Bátorfi, Ross S. Berkowitz, David R. Genest, József Doszpod, Jae Hoon Kim, Vilmos Fulop   +6 more
openaire   +4 more sources

Down-regulation of K cell activity by neutrophils [PDF]

Blood, 1985
Human neutrophils, activated by phorbol-myristate acetate (PMA), (A- neutrophils), were found to suppress lymphocytic killer (K) cell- mediated antibody-dependent cellular cytotoxicity (ADCC). Resting (R) neutrophils, ie, PMA-untreated cells, were completely ineffective. Suppression was optimal when A-neutrophils were added at the beginning of the ADCC
DALLEGRI, FRANCO, PATRONE, FRANCO, Frumento G, BALLESTRERO, ALBERTO, Sacchetti C.   +4 more
openaire   +5 more sources

Network topology drives population temporal variability in experimental habitat networks

Population Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu, J. Angus Webb, William D. Bovill, Elise L. King   +3 more
wiley   +1 more source

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]

, 2018
Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C., Bowler, Nicholas, Craig Hooper, D., Dutta, Anindita, Ertel, Adam, Fedele, Carmine, Forsberg, Flemming, Fortina, Paolo, Gabrilovich, Dmitry I., Harshyne, Larry A., Kean, Rhonda B., Kelly, William K., Kossenkov, Andrew V., Krishn, Shiv Ram, Kurtoglu, Senem, Languino, Lucia R., Liu, Qin, Lu, Huimin, Speicher, David W., Stanczak, Maria, Tang, Hsin-Yao, Wang, Kerith, Weinreb, Paul H., Yu, Lei   +23 more
core   +1 more source

KIR down-regulation on NK cells is associated with down-regulation of activating receptors and NK cell inactivation [PDF]

European Journal of Immunology, 2001
We previously reported that killer cell immunoglobulin-like receptors (KIR) could be down-regulated from the surface of T cells. Here, we show that KIR down-regulation is also induced on the surface of natural killer (NK) cells upon ligand binding.
Lars Karlsson, Frédéric Triebel, Bertrand Huard   +2 more
openaire   +3 more sources

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Synergizing Immune Balance: Curcumin Gold Nanoparticles and Ultrasound Irradiation for Macrophage Down-Regulation

AppliedChem
The multifaceted health benefits of curcumin (Curcuma longa), attributed to its antioxidant, antitumor, and anti-inflammatory activities, have drawn significant scientific attention.
Bruna Henrique Teixeira, Karina de Oliveira Gonçalves, Daniel Perez Vieira, Lilia Coronato Courrol   +3 more
doaj   +1 more source

Decorin Protein is Down-regulated in Non-small Cell Lung Cancer Tissue 
and Significantly Associated with Histological Type

Chinese Journal of Lung Cancer, 2011
Background and objective Decorin is a protein component of the extracellular matrix. It has been proven that decorin plaid an important role in matrix assembly. The protein is also capable of suppressing tumor cell growth.
Yongkai WU, Ting XIAO, Min LI, Ying ZHANG, Yanning GAO, Kelin SUN   +5 more
doaj   +1 more source

M-Calpain Activation Facilitates Seizure Induced KCC2 Down Regulation

Frontiers in Molecular Neuroscience, 2018
Potassium chloride co-transporter 2 (KCC2), a major chloride transporter that maintains GABAA receptor inhibition in mature mammalian neurons, is down-regulated in the hippocampus during epileptogenesis.
Li Wan, Liang Ren, Lulan Chen, Guoxiang Wang, Xu Liu, Benjamin H. Wang, Yun Wang   +6 more
doaj   +1 more source