Results 91 to 100 of about 1,226,398 (302)
Ethnic Differences in Prenatal Screening for Down Syndrome: information, decision-making and participation [PDF]
, 2010 Pregnant women and their partners are increasingly confronted with choices whether or not to participate in prenatal screening for structural, genetic, and chromosomal disorders, such as Down syndrome.
Fransen, M.P. (Mirjam)
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Learning to read in regular and special schools: a follow up study of students with Down Syndrome [PDF]
, 2015 In 2006, a questionnaire was sent to 160 parents of children with Down syndrome in Dutch primary education (special and regular) with a response rate of 76%.
De graaf, Gert, Van Hove, Geert
core
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome [PDF]
, 2012 OBJECTIVES: Although individuals with Down syndrome have considerable oral disease, the prevalence of dental caries in this group is low. The present study aimed to compare known risk factors for dental caries development in children with Down syndrome ...
Azevedo, Álvaro +6 more
core +3 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
International Journal of Turkish Education SciencesThe readiness levels of the university environment play a crucial role in enabling individuals with disabilities to benefit more from higher education.
Özlem Özaydın +4 more
doaj +1 more source
F1000Research, 2016 In this article, we first present a summary of the general assumptions about Down syndrome (DS) still to be found in the literature. We go on to show how new research has modified these assumptions, pointing to a wide range of individual differences at ...
Annette Karmiloff-Smith +11 more
doaj +1 more source
, 2013 People with Down syndrome, a frequent genetic disorder in humans, have increased risk of health problems associated with this condition. One clinical feature of Down syndrome is the increased prevalence and severity of periodontal disease in comparison ...
Cabras, Tiziana +7 more
core +1 more source
A Female Patient with Down Syndrome and Low-Penetrance Leber's Hereditary Optic Neuropathy. [PDF]
, 2014 We present the case of a 19-year-old female with a history of Down syndrome (DS) who was referred to our neuro-ophthalmology clinic for evaluation of Leber's hereditary optic neuropathy (LHON).
Frousiakis, Starleen E +3 more
core +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source