Results 31 to 40 of about 1,249,164 (307)
Seroconversion stages COVID19 into distinct pathophysiological states
eLife, 2021 COVID19 is a heterogeneous medical condition involving diverse underlying pathophysiological processes including hyperinflammation, endothelial damage, thrombotic microangiopathy, and end-organ damage.
Matthew D Galbraith +17 more
doaj +1 more source
Changing Student Teachers' Attitudes Towards Disability and Inclusion [PDF]
, 2003 A total of 274 preservice teacher education students were surveyed at the beginning and end of a one-semester unit on Human Development and Education which combined formal instruction with structured fieldwork experiences.
Campbell, Karyl +2 more
core +2 more sources
Neurobiology of Disease, 2022 Down syndrome (DS) is characterized by chronic neuroinflammation, peripheral inflammation, astrogliosis, imbalanced excitatory/inhibitory neuronal function, and cognitive deficits in both humans and mouse models.
Md. Mahiuddin Ahmed +13 more
doaj +1 more source
The simulation of action disorganisation in complex activities of daily living [PDF]
, 2005 Action selection in everyday goal-directed tasks of moderate complexity is known to be subject to breakdown following extensive frontal brain injury. A model of action selection in such tasks is presented and used to explore three hypotheses concerning ...
Anderson JR +31 more
core +1 more source
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
Nature Communications, 2019 Down syndrome (DS) is caused by trisomy 21 (T21), but the underlying etiology of the related immune and neurological dysfunction is unclear. Here, the authors show that T21 activates the kynurenine pathway via increased interferon receptor copy number ...
Rani K. Powers +20 more
doaj +1 more source
Cell Reports, 2019 Summary: People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions.
Katherine A. Waugh +22 more
doaj +1 more source
Organoids for the Study of Retinal Development and Developmental Abnormalities
Frontiers in Cellular Neuroscience, 2021 The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these three-dimensional organoid models, in turn, have provided unprecedented opportunities for retinal ...
Anne Vielle +7 more
doaj +1 more source
The Perfective Past Tense in Greek Adolescents with Down Syndrome [PDF]
, 2009 This study investigates the ability of a group of eight Greek-speaking adolescents with Down Syndrome (DS) (aged 12.1-18.7) to handle the perfective past tense using an acceptability judgement task.
Clahsen, Harald, Stathopoulou, Nikolitsa
core +1 more source
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source
Nature CommunicationsIndividuals with Down syndrome, the genetic condition caused by trisomy 21, exhibit strong inter-individual variability in terms of developmental phenotypes and diagnosis of co-occurring conditions.
Micah G. Donovan +12 more
doaj +1 more source