Results 31 to 40 of about 4,821,896 (384)
Seroconversion stages COVID19 into distinct pathophysiological states
eLife, 2021 COVID19 is a heterogeneous medical condition involving diverse underlying pathophysiological processes including hyperinflammation, endothelial damage, thrombotic microangiopathy, and end-organ damage.
Matthew D Galbraith +17 more
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Organoids for the Study of Retinal Development and Developmental Abnormalities
Frontiers in Cellular Neuroscience, 2021 The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these three-dimensional organoid models, in turn, have provided unprecedented opportunities for retinal ...
Anne Vielle +7 more
doaj +1 more source
Prevalence of Obstructive Sleep Apnea in Children With Down Syndrome: A Meta-Analysis.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018 STUDY OBJECTIVES To estimate the prevalence of obstructive sleep apnea (OSA) in children with Down syndrome. METHODS Two authors independently searched databases, namely PubMed, MEDLINE, EMBASE, and the Cochrane Review database. The keywords used were "
Chia-Fan Lee +4 more
semanticscholar +1 more source
A critical evaluation of the Down syndrome diagnosis for LB1, type specimen of Homo floresiensis [PDF]
, 2016 The Liang Bua hominins from Flores, Indonesia, have been the subject of intense scrutiny and debate since their initial description and classification in 2004.
Baab, Karen L +6 more
core +4 more sources
Rodent models in Down syndrome research: impact and future opportunities
Disease Models & Mechanisms, 2017 Down syndrome is caused by trisomy of chromosome 21. To date, a multiplicity of mouse models with Down-syndrome-related features has been developed to understand this complex human chromosomal disorder.
Y. Hérault +5 more
semanticscholar +1 more source
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
Nature Communications, 2019 Down syndrome (DS) is caused by trisomy 21 (T21), but the underlying etiology of the related immune and neurological dysfunction is unclear. Here, the authors show that T21 activates the kynurenine pathway via increased interferon receptor copy number ...
Rani K. Powers +20 more
doaj +1 more source
The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities [PDF]
, 2008 The prevalence, and incidence, of mental ill-health in adults with intellectual disabilities and autism were compared with the whole population with intellectual disabilities, and with controls, matched individually for age, gender, ability-level, and ...
A. V. Brereton +67 more
core +1 more source
Haematology of Down syndrome [PDF]
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2007 Down syndrome is a common congenital disorder affecting approximately 1/1000 live births. Newborns and children with Down syndrome may present with many haematological problems. In addition, benign abnormalities of the blood count and blood film, which may manifest at any age, population-based and cancer-based registries and clinical trials suggest ...
Webb, D, Roberts, I, Vyas, P
openaire +4 more sources
Frontiers in Aging Neuroscience, 2021 Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed +17 more
doaj +1 more source
A comparison between the anxiety and hope in mothers having children suffering from autism syndrome and Down syndrome [PDF]
, 2015 Introduction: The present research aimed to compare anxiety and hope between mothers having children suffering from autism syndrome and Down syndrome. Methods: This research used a descriptive-comparative method and the sample of the study included 60
Houda, Michal, Kaňková, Vlasta
core +2 more sources