Results 261 to 270 of about 453,301 (335)

AminoTricomplex Therapy in Advanced Triple-Negative Breast Cancer: A Translational Study Linking Survivin Downregulation, Cystatin C Upregulation, and MT1 Receptor Re-Expression to Clinical Outcomes [PDF]

Alexandre Tavartkiladze, Gaiane Simonia, Rüssel J. Reiter, Ruite Lou, Nana Okrostsvaridze, Dinara Kasradze, Pati Revazishvili, Irine Andronikashvili, Pirdara Nozadze, Givi Tavartkiladze, Rusudan Khutsishvili, Tatia Potskhoraia   +11 more
openalex   +1 more source

Circular RNAs hsa_circ_0001438 and hsa_circ_0000417 are downregulated and upregulated, respectively, in hepatocellular carcinoma

Circular RNAs hsa_circ_0001438 and hsa_circ_0000417 are downregulated and upregulated, respectively, in hepatocellular carcinoma
Author: Sachiko Imanishi, Shoko Nagata, Toshitsugu Fujita, Hodaka Fujii Citation: International Journal of Experimental Pathology 103(6):245-251, 2022 ...
openaire  

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Comparative Proteomic Analysis of <i>Acremonium chrysogenum</i> Strains: Key Changes Converting the Wild-Type Strain into Antibiotic Cephalosporin C Biofactory. [PDF]

J Fungi (Basel)
Zhgun AA, Dumina MV, Beletsky AV, Kopylov AT, Zgoda VG.   +4 more
europepmc   +1 more source

Inhibition of Proliferation and Induction of Autophagy by Atorvastatin in PC3 Prostate Cancer Cells Correlate with Downregulation of Bcl2 and Upregulation of miR-182 and p21

, 2013
Xinjian Peng, Wenping Li, Liang Yuan, Rajendra G. Mehta, Levy Kopelovich, David L. McCormick   +5 more
openalex   +2 more sources

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Diagnostic, Prognostic, and Immunomodulatory Roles of Prostaglandin E Receptor 1 (PTGER1): A Pan-Cancer Study. [PDF]

Cureus
Suliman R, Alfaki M.
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Age-Related Transcriptomic Changes in the Vermiform Appendix. [PDF]

Int J Mol Sci
Quien D, Korac-Prlic J, Vilović K, Pogorelić Z, Boric M, Barcot O, Degoricija M.   +6 more
europepmc   +1 more source

Upregulation of adrenocorticotrophic hormone in the corticotrophs and downregulation of surface receptors and antigens on the macrophages in the adenohypophysis following an exposure to high altitude

, 2002
Charanjit Kaur, Jeffrey M. Singh, Caixia Peng, Eng‐Ang Ling   +3 more
openalex   +2 more sources