Results 271 to 280 of about 462,684 (373)

Corrigendum to “The active phthalate metabolite, DHEP, induces proliferation and metastasis of prostate cancer cells via upregulation of β-catenin and downregulation of KLF7” [Bioorganic Chem., 141 (2023) 106864]

, 2023
Hecheng Li, Jianping Li, Yubo Ma, Ziming Wang, Zihe Peng, Hang Xu, Hang Bi, Shaik Althaf Hussain, Zhaolun Li   +8 more
openalex   +1 more source

CD30 Downregulation, MMAE Resistance, and MDR1 Upregulation Are All Associated with Resistance to Brentuximab Vedotin

Molecular Cancer Therapeutics, 2015
Robert Chen, Jessie Hou, E. Newman, Young L. Kim, C. Donohue, Xueli Liu, Sandra H. Thomas, S. Forman, S. Kane   +8 more
semanticscholar   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Human Multi-Organoid Platform to Model Immune Dynamics in Cardiac Injury and Disease. [PDF]

Circ Res
Reyat JS, Shen Y, Poologasundarampillai G, Poologasundarampillai G, Moetazedian A, Rayes J, Khan AO.   +6 more
europepmc   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Modulating cortical excitability and cortical arousal by pupil self-regulation. [PDF]

Nat Commun
Weijs ML, Missura S, Potok-Szybińska W, Bächinger M, Badii B, Carro-Domínguez M, Wenderoth N, Meissner SN.   +7 more
europepmc   +1 more source

TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5

Laboratory Investigation, 2015
Matthew McMillin, Gabriel Frampton, Andrew P. Seiwell, Nisha Patel, Amber N Jacobs, S. DeMorrow   +5 more
semanticscholar   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Metallothioneins in the Pathogenesis of Liver Diseases: A Review. [PDF]

Int J Hepatol
Nowicka AA, Gomułkiewicz A, Serafińska S, Simon KA, Dzięgiel P.   +4 more
europepmc   +1 more source

Amarogentin Induces Apoptosis of Liver Cancer Cells via Upregulation of p53 and Downregulation of Human Telomerase Reverse Transcriptase in Mice

Technology in Cancer Research and Treatment, 2017
Chun Huang, Runqin Li, Yinglin Zhang, J. Gong   +3 more
semanticscholar   +1 more source