Results 81 to 90 of about 124,618 (258)

Doxycycline as STI PEP

This paper answers these questions: What is Doxycycline as STI PEP?; How effective is Doxycycline as STI PEP?; Can anyone use Doxycycline as STI PEP?; What do I need to know about Doxycycline as STI PEP and STI testing?; How can I protect myself from ...
South Carolina Department of Health and Environmental Control
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Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

Advanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu, Xin Chen, Tao Sun, Jianqi Wu, Haixu Yan, Xing Liu, Hongda Lin, Xiangyu Wang, Ziao Xiao, Yang Xu, Qiang Fu, Peng Cheng, Wen Cheng, Anhua Wu   +13 more
wiley   +1 more source

Sex Transm Dis [PDF]

Background:Sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia have significantly increased over the past decade in the United States.

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One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

Advanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He, Liang Zhong, Tianzhi Chen, Yaxuan Yan, Xinze Chen, Runbo Li, Yingjie Wang, Yadi Teng, Minglei Zhi, Meng Wang, Jinying Zhang, Fan Zhao, Dengfeng Gao, Suying Cao, Jianyong Han   +14 more
wiley   +1 more source

Low-dose doxycycline inhibits hydrogen peroxide-induced oxidative stress, MMP-2 up-regulation and contractile dysfunction in human saphenous vein grafts

, 2019
Mazen Saeed,1 Mehmet Zuhuri Arun,2 Mehmet Guzeloglu,3 Ceylan Onursal,1 Goksel Gokce,2 Ceren Gonen Korkmaz,2 Buket Reel21Ege University, Faculty of Pharmacy, Department of Pharmacology, 35100 Bornova, Izmir, Turkey; 2Ege University, Faculty of Pharmacy ...
Reel B, Arun MZ, Onursal C, Saeed M, Guzeloglu M, Gokce G, Korkmaz CG   +6 more
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Bio-Equivalence of Doxycycline in Two Preparations in Broiler Chickens [PDF]

, 2015
The present study was designed to investigate the bio-equivalence of doxycycline in Dolistin® and Colidox® at a dose rate of 10 mg doxycycline/kg of body weight in 48 clinically normal broiler chickens.
Abdelrazzag Elmajdoub
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ALDH2 Suppresses Ferroptosis and Promotes Bortezomib Resistance in Multiple Myeloma Through the KEAP1‐NRF2 Feedback Loop

Advanced Science, EarlyView.
ALDH2, which is overexpressed in multiple myeloma, competitively binds KEAP1 to stabilize NRF2 by blocking its ubiquitin‐proteasomal degradation. Stabilized NRF2 translocates into the nucleus to upregulate the expression of GPX4. In parallel, NRF2 binds to the ALDH2 promoter to regulate its transcription, forming a positive feedback loop that represses
Ruonan Shao, Chengcheng Liu, Xinpei Deng, Jindong Xie, Wenjian Liu, Bin Yang, Lingrui Liu, Cailu Song, Lei Li, Hua Wang, Hailin Tang   +10 more
wiley   +1 more source

Chlorogenic acid attenuates tet (X)-mediated doxycycline resistance of Riemerella anatipestifer

Frontiers in Veterinary Science
IntroductionThe increasing resistance of R. anatipestifer has posed a significant threat to the poultry industry in recent years. The tet gene is the primary determinant of tetracycline resistance in numerous bacteria, and the enzyme modification gene ...
Yuwen Han, Min Li, Dehai Su, Shiyu Xiong, Youshu Feng, Qin Deng, Huanzhong Ding   +6 more
doaj   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

Fibroblasts isolated from a SCNT-TG piglet express eGFP when cultured in the presence of doxycycline.

, 2014
(A) Fibroblasts isolated from a SCNT-TG piglet were cultured in the presence of doxycycline for 1–3 days and then in the absence of doxycycline for a further 1–2 days. Cells were examined by bright field and fluorescence microscopy.
Yubyeol Jeon (509390), Mo-Sun Kwon (509392), Teoan Kim (509393), Sang-Hwan Hyun (295152), Sung-Hyun Lee (509391), Nam-Hyung Kim (293371), Xiang-Shun Cui (293370), Yong-Xun Jin (509389)   +7 more
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