Results 81 to 90 of about 25,207 (238)

Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms. [PDF]

, 2007
PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
core   +1 more source

Early syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin

Journal of Infection in Developing Countries, 2014
Introduction: Benzathine penicillin G is the treatment of choice for syphilis, but doxycycline and tetracycline are effective second-line treatments. The objective of this study was to assess the serological response to treatment for early syphilis with ...
Jun Li, He-Yi Zheng
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Doxycycline as STI PEP

This paper answers these questions: What is Doxycycline as STI PEP?; How effective is Doxycycline as STI PEP?; Can anyone use Doxycycline as STI PEP?; What do I need to know about Doxycycline as STI PEP and STI testing?; How can I protect myself from ...
South Carolina Department of Health and Environmental Control
core   +3 more sources

Dental staining after doxycycline use in children [PDF]

, 2017
Background: The use of doxycycline has been avoided before 8 years of age due to known dental staining caused by tetracyclines, although doxycycline differs from classical tetracyclines in many ways. Doxycycline is still an important antimicrobial agent,
Peltola, Ville, Tuire Lähdesmäki, Lahdesmaki, Tuire, Nurmi, Mirka, Poyhonen, Heidi, Ruuskanen, Olli, Heidi Pöyhönen, Satu Alaluusua, Ville Peltola, Olli Ruuskanen, Mirka Nurmi, Alaluusua, Satu   +11 more
core   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax [PDF]

International audienceABSTRACT Testing Plasmodium vivax antimicrobial sensitivity is limited to ex vivo schizont maturation assays, which preclude determining the IC50s of delayed action antimalarials such as doxycycline.
Christensen, Peter, Cinzah, Rosy, Kyle, Dennis, Cook, Gregory M., Yen Chua, Adeline Chiew, Russell, Bruce, Chua, Adeline Chiew Yen, Rénia, Laurent, Aung, Htin Lin, Kaneko, Osamu, Matheson, Jessica, Snounou, Georges, Cook, Gregory, Kyle, Dennis E., Suwanarusk, Rossarin, https://orcid.org/, Bifani, Pablo   +16 more
core   +1 more source