Results 61 to 70 of about 25,207 (238)

PROPHYLACTIC ADMINISTRATION OF DOXYCYCLINE REDUCES CENTRAL VENOUS CATHETER INFECTIONS IN PATIENTS UNDERGOING HEMATOPOIETIC CELL TRANSPLANTATION

Mediterranean Journal of Hematology and Infectious Diseases, 2013
Hematopoietic stem cells are usually transfused through a central venous catheter (CVC), which also facilitates administration of medications and intravenous fluids.
Mohamed Kharfan-Dabaja, Mohamed Baydoun, Zaher Otrock, Samar Okaily, Rita Nehme, Racha Abu-Chahine, Ali Hamdan, Samar Noureddine, Souha Kanj, Zeina Kanafani, Ali Bazarbachi   +10 more
doaj   +1 more source

Efficiency of a Tetracycline-Adjuvant Combination Against Multidrug Resistant Pseudomonas aeruginosa Tunisian Clinical Isolates

Antibiotics, 2020
The growing number of multidrug resistant strains in Tunisia has become a serious health concern contributing to high rate of mortality and morbidity. Since current antibiotics are rapidly becoming ineffective, novel strategies to combat resistance are ...
Azza Troudi, Meha Fethi, Mohamed Selim El Asli, Jean Michel Bolla, Naouel Klibi, Jean Michel Brunel   +5 more
doaj   +1 more source

Evaluation of the doxycycline release from AH26 sealer-doxycycline combination: An ex vivo study [PDF]

, 2011
INTRODUCTION: The purpose of this ex vivo study was to determine the releasing characteristics and doxycycline dentinal diffusion of AH26 sealer-doxycycline combination from apical 3mm of tooth root and apical foramen.
Noushin Shokouhinejad, Yazdi, Kazem Ashofteh, Moazeni, Esmaeil, Kazem Ashofteh Yazdi, Shokouhinejad, Noushin, Mirzayi Rad, Sina, Sina Mirzayi Rad, Esmaeil Moazeni   +7 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Azithromycin and doxycycline intravenous and oral administrations before and after prescriber-facing alert for intravenous fluid conservation

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: Intravenous (IV) to oral (PO) antimicrobial stewardship initiatives can be implemented by various healthcare providers in conjunction with clinical decision support tools. Our study evaluated the impact of a prescriber-facing IV to PO alert on
Jennifer Dela-Pena, Jill Wesolowski, Gretchen Sacha, Andrea M. Pallotta   +3 more
doaj   +1 more source

The Wound Healing Effect of Doxycycline after Corneal Alkali Burn in Rats

Journal of Ophthalmology, 2019
Purpose. To evaluate the wound healing effect of doxycycline and its underlying mechanisms in a rat model of corneal alkali burn. Methods. Male SD rats were administered 1.0 N NaOH in the right cornea for 25 seconds and randomly divided into the ...
Qiong Yi, Wen-jin Zou
doaj   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

Advanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu, Shihui Shen, Dongxia Li, Peilin Shi, Jiaming Xu, Tongxin Lv, Yingying Du, Jingwei Zhang, Bo Yang, Hansen Chen, Zhuoya Peng, Wenjie Ren, Lu Zhang, Sheng Cheng, Tongjin Yin, Wencai Sheng, Lei Li, Juan Wu, Qingcheng Yang, Shuogui Xu, Wei Zheng   +20 more
wiley   +1 more source

Efek Doxycycline dosis rendah terhadap jumlah serat kolagen tikus wistar yang diinduksi agregatebacter actinomycetemcomitans. [PDF]

, 2011
Background. Periodontitis is characterized by periodontal tissue destruction such as destruction of collagen fibers, periodotal ligament and alveolar bone that cause tooth mobility.
Erni Maduratna, Setiawati
core   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

The Effect of Doxycycline on Glomerulosclerosis in 5/6 Renal Ablation Nephropathy

, 2020
Objectives:The beneficial effect of matrix metalloproteinases (MMP) inhibitors in renal diseases has been reported. Their effect in segmental sclerosis is unknown.
Ali Çelik, Kahraman, Devrim, Sulen Sarıoğlu, Çelik, Ali, Devrim Kahraman, Funda Sağlam, Zahide Çavdar, Sarıoğlu, Sülen, Sağlam, Funda, Kolatan, Hatice Efsun, Osman Yılmaz, Efsun Kolatan, Yılmaz, Osman, Çavdar, Zahide   +13 more
core   +1 more source