Results 31 to 40 of about 246,662 (243)
End‐to‐End Crystal Structure Prediction from Powder X‐Ray Diffraction
Advanced SciencePowder X‐ray diffraction (PXRD) is a prevalent technique in materials characterization. While the analysis of PXRD often requires extensive human manual intervention, and most automated method only achieved at coarse‐grained level. The more difficult and
Qingsi Lai +11 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The classification of dp-minimal and dp-small fields
Journal of the European Mathematical Society, 2022 Continuing the work of Johnson (2018), we classify the pure fields and pure valued fields of dp-rank 1, up to elementary equivalence. In the process, we give a few new examples of dp-minimal fields. Specializing to the case of dp-small fields, we prove that dp-small fields and VC-minimal fields are all algebraically closed or real ...
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Generalized DP-colorings of graphs
Discrete Mathematics, 2023 Extension of the original version from simple graphs to graphs in general.
Alexandr V. Kostochka +2 more
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A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Order in the DP! On word order and the structure of the DP
LSA Annual Meeting Extended Abstracts, 2015 Novel observations show Cinque’s (2005) phrasal movement proposal makes correct predictions on the grammaticality of word orders in Lebanese Arabic noun phrases. Adding an adjective yields grammatical orders Cinque (2005) cannot derive. We show that assuming an additional merge position—either for demonstratives or for numerals—derives the orders ...
Ouwayda, Sarah, Shlonsky, Ur
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Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods
MedCommmRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells. This technology offers notable advantages including rapid development cycles, diverse therapeutic applications ...
Ruichu Gu +5 more
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source