Results 41 to 50 of about 1,756,294 (271)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Outcomes and risk score for distal pancreatectomy with celiac axis resection (DP-CAR) : an international multicenter analysis [PDF]

, 2019
Background: Distal pancreatectomy with celiac axis resection (DP-CAR) is a treatment option for selected patients with pancreatic cancer involving the celiac axis.
Adham, Mustapha, Bassi, Claudio, Berrevoet, Frederik, Besselink, Marc G, Boggi, Ugo, Busch, Olivier R, Cesaretti, Manuela, Dalla Valle, Raffaele, Darnis, Benjamin, Del Chiaro, Marco, Diener, Markus K, Dumitrascu, Traian, Friess, Helmut, Fusai, Giuseppe K, Gerritsen, Sarah L, Gruetzmann, Robert, Hackert, Thilo H, Hirono, Seiko, Hogg, Melissa E, Ivanecz, Arpad, Javed, Ammar A, Karayiannakis, Anastasios, Kawai, Manabu, Kleeff, Jorg, Klompmaker, Sjors, Labori, Knut J, Lesurtel, Mickael, Lombardo, Carlo, Lopez-Ben, Santiago, Mabrut, Jean-Yves, Miyazawa, Motoki, Moser, A James, Niesen, Willem, Okada, Ken-ichi, Pardo, Fernando, Perinel, Julie, Peters, Niek A, Popescu, Irinel, Prasad, Raj, Roeyen, Geert, Salvia, Roberto, Sauvanet, Alain, Sturesson, Christian, Teresa Albiol, M, Van Gulik, Thomas M, Van Hilst, Jony, Weiss, Matthew J, Wolfgang, Christopher L, Yamaue, Hiroki, Zeh, Herbert J, Zureikat, Amer H   +50 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

End‐to‐End Crystal Structure Prediction from Powder X‐Ray Diffraction

Advanced Science
Powder X‐ray diffraction (PXRD) is a prevalent technique in materials characterization. While the analysis of PXRD often requires extensive human manual intervention, and most automated method only achieved at coarse‐grained level. The more difficult and
Qingsi Lai, Fanjie Xu, Lin Yao, Zhifeng Gao, Siyuan Liu, Hongshuai Wang, Shuqi Lu, Di He, Liwei Wang, Linfeng Zhang, Cheng Wang, Guolin Ke   +11 more
doaj   +1 more source

Dp Branes in PP-wave Background [PDF]

, 2002
Dirichlet p-branes in the background of pp waves are constructed using the massive Green-Schwarz worldsheet action for open strings. These branes are localized at the origin and only for $p=7, 5, 3$ preserve half the supersymmetries.
Aharony, Alishahiha, Atish Dabholkar, Balasubramanian, Berenstein, Berenstein, Billo, Blau, Blau, Chu, Cvetič, Cvetič, Das, Floratos, Gomis, Green, Gubser, Gursoy, Güven, Hatsuda, Itzhaki, Kim, Maldacena, McGreevy, Metsaev, Metsaev, Michelson, Penrose, Polchinski, Shahrokh Parvizi, Takayanagi, Witten, Zayas   +32 more
core   +2 more sources

Amazing DPs

Semantics and Linguistic Theory, 2008
No abstract.
Elena Castroviejo, Magdalena Schwager
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

1950 Genel Seçimlerinde Van

Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2021
1945 yılından itibaren tek parti sisteminin popülaritesini kaybetmesi üzerine Türkiye’de çok partili demokrasi yolunda hızlı adımlar atılmaya başlandı.
Cevdet Teke
doaj  

Inter-Brane Potential and the Decay of a non-BPS-D-brane to Closed Strings

, 2003
We calculate the potential for $Dp-\Dbar p$ pair and show that the coincident $Dp-\Dbar p$ system has $(11-p)$ tachyonic modes, with $(9-p)$ of them due to radiative corrections. We propose that the decay width of an unstable non-BPS-$Dp$-brane to closed
Bachas, Bergman, Burgess, Chen, Constable, Craps, Dvali, Fujita, Gaiotto, Garcia-Bellido, Gibbons, Gutperle, Jones, Karczmarek, Kleban, Lambert, Larsen, Maloney, Marcus, Moeller, Okuda, Polchinski, Rey, S.-H.Henry Tye, Sarangi, Saswat Sarangi, Sen, Sen, Sen, Sen, Sen, Strominger, Weinberg, Yi   +33 more
core   +2 more sources

Non-Relativistic Non-BPS Dp-brane [PDF]

, 2006
We construct non-relativistic non-BPS Dp-brane action. Then we will study the properties of the tachyon kink solution on its world-volume.
Aganagic, Bergshoeff, Bergshoeff, Bergshoeff, Billo, Brugues, Cederwall, Cederwall, Danielsson, Danielsson, Fotopoulos, Garousi, Gomis, Gomis, Gomis, Gomis, Gopakumar, Gopakumar, Harmark, Horava, J. Klusoň, Kamimura, Kennedy, Kluson, Kluson, Kluson, Kraus, Kutasov, Niarchos, Okuyama, Sakaguchi, Seiberg, Seiberg, Sen, Sen, Sen, Sen, Sen, Sen, Takayanagi, Witten   +40 more
core   +3 more sources