Results 51 to 60 of about 1,756,294 (271)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Quantifying Differential Privacy under Temporal Correlations
, 2017 Differential Privacy (DP) has received increased attention as a rigorous privacy framework. Existing studies employ traditional DP mechanisms (e.g., the Laplace mechanism) as primitives, which assume that the data are independent, or that adversaries do ...
Cao, Yang +3 more
core +1 more source
Free Energies and Probe Actions for Near-horizon D-branes and D1 + D5 System [PDF]
, 1999 By working with the free energy for the type II supergravity near-horizon solution of N coincident non-extremal Dp-branes we study the transitions among the non-conformal Dp-brane system, the perturbative super Yang-Mills theory and a certain system ...
Dijkgraaf R. +4 more
core +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods
MedCommmRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells. This technology offers notable advantages including rapid development cycles, diverse therapeutic applications ...
Ruichu Gu +5 more
doaj +1 more source
Non-threshold (F, Dp) bound states [PDF]
, 1999 In the previous paper [hep-th/9904112], we argued that there exist BPS bound states of Dp branes carrying certain units of quantized constant electric field for every $p$ (with $1 \le p \le 8$).
Arfaei +24 more
core +2 more sources
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Double parton interactions as a background to associated HW production at the Tevatron
, 2010 In this paper we study events with W+jets final state, produced in double parton (DP) interactions, as a background to the associated Higgs boson (H) and W production, with H->bbar decay, at the Tevatron.
Bandurin, Dmitry +2 more
core +1 more source
Does the Use of Dihydroartemisinin-Piperaquine in Treating Patients with Uncomplicated falciparum Malaria Reduce the Risk for Recurrent New falciparum Infection More Than Artemether-Lumefantrine? [PDF]
, 2014 Malaria contributes significantly to the global disease burden. The World Health Organization recommended the use of artemisinin-based combination therapies (ACTs) for treatment of uncomplicated falciparum malaria a decade ago in response to problems of ...
Akpaloo, W., Purssell, E.
core +4 more sources