Results 41 to 50 of about 1,766,311 (319)
Epidemic processes with immunization
, 2003 We study a model of directed percolation (DP) with immunization, i.e. with different probabilities for the first infection and subsequent infections. The immunization effect leads to an additional non-Markovian term in the corresponding field theoretical
A.S. Perelson +40 more
core +1 more source
SOAP3-dp: Fast, Accurate and Sensitive GPU-based Short Read Aligner [PDF]
, 2013 To tackle the exponentially increasing throughput of Next-Generation Sequencing (NGS), most of the existing short-read aligners can be configured to favor speed in trade of accuracy and sensitivity. SOAP3-dp, through leveraging the computational power of
Chang Yu +16 more
core +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
End‐to‐End Crystal Structure Prediction from Powder X‐Ray Diffraction
Advanced SciencePowder X‐ray diffraction (PXRD) is a prevalent technique in materials characterization. While the analysis of PXRD often requires extensive human manual intervention, and most automated method only achieved at coarse‐grained level. The more difficult and
Qingsi Lai +11 more
doaj +1 more source
Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2021 1945 yılından itibaren tek parti sisteminin popülaritesini kaybetmesi üzerine Türkiye’de çok partili demokrasi yolunda hızlı adımlar atılmaya başlandı.
Cevdet Teke
doaj
Semantics and Linguistic Theory, 2008 No abstract.
Elena Castroviejo, Magdalena Schwager
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A Simple Nonlinearity-Tailored Probabilistic Shaping Distribution for Square QAM [PDF]
, 2017 A new probabilistic shaping distribution that outperforms Maxwell-Boltzmann is studied for the nonlinear fiber channel. Additional gains of 0.1 bit/symbol MI or 0.2 dB SNR for both DP-256QAM and DP-1024QAM are reported after 200 km nonlinear fiber ...
Alvarado, Alex +8 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source