Results 51 to 60 of about 1,766,311 (319)

Toward a more realistic holographic QCD model [PDF]

open access: yes, 2008
By matching the $Dp-Dq$ system in type II superstring theory with the Regge trajectories of vector and axial-vector meson spectra, a possible 5-dimension metric of a $Dp-Dq$ soft-wall model has been determined.
Huang, Mei, Yan, Qi-shu, Yang, Yi
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

open access: yesMedComm
mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells. This technology offers notable advantages including rapid development cycles, diverse therapeutic applications ...
Ruichu Gu   +5 more
doaj   +1 more source

On the tau-functions of the Degasperis-Procesi equation

open access: yes, 2012
The DP equation is investigated from the point of view of determinant-pfaffian identities. The reciprocal link between the Degasperis-Procesi (DP) equation and the pseudo 3-reduction of the $C_{\infty}$ two-dimensional Toda system is used to construct ...
Bao-Feng Feng   +19 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Gain without Pain: Offsetting DP-injected Nosies Stealthily in Cross-device Federated Learning [PDF]

open access: green, 2021
Wenzhuo Yang   +6 more
openalex   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A pre-trained deep potential model for sulfide solid electrolytes with broad coverage and high accuracy

open access: yesnpj Computational Materials
Solid electrolytes with fast ion transport are crucial for solid state lithium metal batteries. Chemical doping has been the most effective strategy for improving ion condictiviy, and atomistic simulation with machine-learning potentials helps optimize ...
Ruoyu Wang   +8 more
doaj   +1 more source

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