Results 41 to 50 of about 85,599,608 (253)
, 2013 DPP-4 activity was measured 24 h after administration of the respective compounds (N = 13–17 per DPP-4 inhibitor group, control N = 57; no difference was made between sham-operated rats and 5/6N groups). All drugs showed a significant inhibition of DPP-4
Berthold Hocher (311916) +8 more
core +1 more source
DPP-4 inhibitor dose selection according to manufacturer specifications: A contemporary experience from UK general practice [PDF]
, 2019 Recently, 2 dipeptidyl peptidase-4 (DPP-4) inhibitors, sitagliptin and saxagliptin, adjusted dosing specification from creatinine clearance to glomerular filtration rate, more typically reported in routine laboratory tests.
Tebboth, Abigail +5 more
core +1 more source
Gemigliptin: An Update of Its Clinical Use in the Management of Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2016 Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral antidiabetic agent for the treatment of type 2 diabetes mellitus. They increase endogenous levels of incretin hormones, which stimulate glucose-dependent insulin secretion, decrease ...
Sung-Ho Kim +3 more
doaj +1 more source
DPP-4 mediating insulin resistance and lipogenesis.
, 2022 HepG2 cells were incubated with OAPA and 50 μM of linagliptin for 24 h, and then analyzed the cytotoxicity (A), DPP-4 activity (B), the expression of FAS (C) and insulin resistance (D) signals. For the cytotoxicity and DPP-4 activity, data were presented
Yaw-Bee Ker (515378) +5 more
core +1 more source
Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Sitagliptin: the world’s first DPP-4 inhibitor
Медицинский совет, 2019 The prevalence of T2D is steadily increasing annually, which resulted in an active search for a way to control the disease. The last decade has seen a rise in the number of new groups of glucose-lowering drugs, which not only proved effective in the ...
N. A. Petunina +4 more
doaj +1 more source
, 2018 To assess the efficacy and safety of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors plus a dipeptidyl peptidase‐4 (DPP‐4) inhibitor in patients with type 2 diabetes mellitus (T2DM), we performed a systematic review and meta‐analysis of 14 randomized ...
Huilin Tang +7 more
core +1 more source
Advanced Functional Materials, EarlyView.Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Bullvalene is a fluxional molecule capable of adopting numerous conformations spontaneously; just like a Rubik's Cube. In this paper, we explore the incorporation of bullvalene into the backbone of a highly rigid conjugated polymer semiconductor and observe that the inherent fluxionality reduces average crystallite size.
Shine H. Huang +7 more
wiley +2 more sources