Results 91 to 100 of about 40,250 (264)

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

Strengthened inter‐chain π–π contacts in amorphous diketopyrrolopyrrole polymers for robust flexible organic thin‐film transistors

open access: yesFlexMat, EarlyView.
Vinylene‐linked DPP polymers with expanded thiophene donors achieve strengthened interchain π‐π stacking in near‐amorphous films, enabling high charge mobility and outstanding mechanical stability for flexible organic thin‐film transistors. Abstract Flexible organic thin‐film transistors (OTFTs) based on multi‐vinylene‐linked diketopyrrolopyrrole (DPP)
Yanlin Chen   +11 more
wiley   +1 more source

Material design strategies for flexible n‐type polymer semiconductors

open access: yesFlexMat, EarlyView.
This Perspective surveys recent progress in flexible n‐type polymer semiconductors, emphasizing the interplay between molecular design and microstructure control. It outlines strategies including backbone and side‐chain engineering, multilevel microstructure optimization, to maintain charge‐transport pathways under mechanical deformation.
Xiao‐Yan Zhang   +4 more
wiley   +1 more source

Fluorene‐based blue emitters: On the path to electrically pumped organic lasers

open access: yesFlexMat, EarlyView.
Electrically pumped efficient operation remains unrealized, a major challenge in optoelectronics. Fluorene‐based blue‐emitting semiconductors are promising gain media, thanks to their structural tunability and favorable emission properties. This review summarizes recent advances, highlights their reliability and versatility in lasing, and outlines key ...
Yong Yan   +7 more
wiley   +1 more source

Recent advances in organic broad‐spectrum photodetection materials and devices

open access: yesInfoMat, EarlyView.
Graphical Abstract This review systematically outlines the evolution of organic photodetectors from fullerene‐based to advanced non‐fullerene acceptors, highlighting how molecular engineering (e.g., D–A, quinoidal, and A‐D‐A′‐D‐A architectures) extends spectral response into the short‐wave infrared region.
Yilin Zhao   +3 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Mineral‐targeted alkaline phosphatase improves bone graft‐mediated alveolar bone defect healing in mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri   +4 more
wiley   +1 more source

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