Results 51 to 60 of about 19,701 (225)

DPP4 activity and patient characteristics.

, 2020
DPP4 activity and patient characteristics.
Moritz Lindquist Liljeqvist (4576801), Malin Kronqvist (6822239), Joy Roy (3439511), Christina Villard (8350929), Mariette Lengquist (571206), Rebecka Hultgren (6743690), Linnea Eriksson (8350926)   +6 more
core   +1 more source

Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron

Nature Chemical Biology, 2023
Serine hydrolases play important roles in signaling and human metabolism, yet little is known about their functions in gut commensal bacteria. Using bioinformatics and chemoproteomics, we identify serine hydrolases in the gut commensal Bacteroides thetaiotaomicron that are specific to the Bacteroidetes phylum.
Laura J. Keller, Taylor H. Nguyen, Lawrence J. Liu, Brianna M. Hurysz, Markus Lakemeyer, Matteo Guerra, Danielle J. Gelsinger, Rachael Chanin, Nhi Ngo, Kenneth M. Lum, Franco Faucher, Phillip Ipock, Micah J. Niphakis, Ami S. Bhatt, Anthony J. O’Donoghue, Kerwyn Casey Huang, Matthew Bogyo   +16 more
openaire   +3 more sources

Measurement of DPP4 activity and protein expression.

, 2013
DPP4 activity of (A) total heart and (B) cardiomyocyte protein were measured in wild-type and DPP4-deficient rats. (C)DPP4 expression was measured in two kinds of cardiomoyocytes by using western blot.
Hui-Chun Ku (286915), Ming-Jai Su (286917), Wen-Pin Chen (286916)   +2 more
core   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Mental Health Disorders in Type 2 Diabetes: Active Comparator, New User Cohort Study. [PDF]

Diabetes Obes Metab
ABSTRACT Aims We evaluated the risk of mental health disorders among glucagon‐like peptide‐1 receptor agonist (GLP1RA) users compared with users of dipeptidyl peptidase‐4 (DPP‐4) inhibitors and sodium‐glucose cotransporter‐2 (SGLT2) inhibitors. Materials and Methods We conducted a nationwide, active‐comparator new‐user cohort study using the Korean ...
Kim C, Kim S, Lee DY, Han E, Lee YH, You SC.   +5 more
europepmc   +2 more sources

DPP4 rs13015258 A>C, DPP4 rs17848916 T>G, DPP4 rs41268649 G>A, DPP4 rs17574 T>C genotype and treatment outcome in Thai patients with CHC genotype1 infection.

, 2015
DPP4 rs13015258 A>C, DPP4 rs17848916 T>G, DPP4 rs41268649 G>A, DPP4 rs17574 T>C genotype and treatment outcome in Thai patients with CHC genotype1 infection.
Wattana Sukeepaisarnjaroen (279136), Yong Poovorawan (39511), Pisit Tangkijvanich (513614), Rujipat Wasitthankasem (732723), Sombat Treeprasertsuk (792133), Sirinporn Suksawatamnuay (792132), Kessarin Thanapirom (792131), Piyawat Komolmit (279133), Panarat Thaimai (792134)   +8 more
core   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

DPP4 Regulates DHCR24-Mediated Cholesterol Biosynthesis to Promote Methotrexate Resistance in Gestational Trophoblastic Neoplastic Cells

Frontiers in Oncology, 2021
Metabolic reprogramming could promote cellular adaptation in response to chemotherapeutic drugs in cancer cells. Herein, we aimed to characterize the metabolomic profiles regulated by Dipeptidyl Peptidase 4 (DPP4) in methotrexate (MTX)-resistant ...
Weijie Yuan, Weijie Yuan, Wenjing Yong, Jing Zhu, Dazun Shi   +4 more
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source