Functional studies of human variants in C. elegans link iron metabolism to DPD deficiency and 5-FU sensitivity. [PDF]
GeneticsLi X +3 more
europepmc +1 more source
Practical guide to implementing pre-emptive pharmacogenetic screening in routine pediatric oncology care. [PDF]
PharmacogenomicsBernsen EC +8 more
europepmc +1 more source
Editorial: Updates on pharmacogenomics role in cancer chemotherapy. [PDF]
Front PharmacolElbarbry F.
europepmc +1 more source
Leveraging the molecular insights and therapeutic potential of diet-derived-flavonoids against pancreatic ductal adenocarcinoma. [PDF]
Front PharmacolSankarasubramanian S, Perumal N.
europepmc +1 more source
Response to “DPYD genotyping panels: Impact of population diversity”
Clinical and Translational ScienceAndrea Gaedigk +4 more
openaire +3 more sources
Association of DPYD rs4294451, plasma uracil concentration, and sex with 5-fluorouracil exposure in patients with gastrointestinal cancer. [PDF]
Cancer Chemother PharmacolBrooks GA +12 more
europepmc +1 more source
Factors influencing pharmacokinetics of 5-fluorouracil in cancer patients: a systematic review of population pharmacokinetic models. [PDF]
Eur J Clin PharmacolSuthahar T +6 more
europepmc +1 more source
Managing Secondary Findings from Germline Pharmacogenomic Testing. [PDF]
J Pers MedLee YM, Kearney E, Kisor DF, Farrell CL.
europepmc +1 more source
Analytical Validation of an Annotation Tool for WGS-Based Pharmacogenomics: Preparing for Clinical Implementation in Pediatric Oncology. [PDF]
Clin Transl SciDiekstra MHM +9 more
europepmc +1 more source
DPYD genotyping panels: Impact of population diversity
Clinical and Translational Scienceopenaire +3 more sources